Abstract：
Gallic acid (GA) is one of the most important polyphenols, being widely used in the food, cosmetic, and pharmaceutical industries due to its biological effects such as antioxidant, antibacterial, anticancer, antiviral, anti-inflammatory, and cardioprotective properties. Hence, simple, fast, and sensitive determination of GA is of particular importance. Considering the fact that GA is an electroactive compound, electrochemical sensors offer great potential for GA quantitation due to their fast response time, high sensitivity, and ease of use. A simple, fast, and sensitive GA sensor was fabricated on the basis of a high-performance bio-nanocomposite using spongin as a natural 3D polymer, atacamite, and multi-walled carbon nanotubes (MWCNTs). The developed sensor showed an excellent response toward GA oxidation with remarkable electrochemical features due to the synergistic effects of 3D porous spongin and MWCNTs, which provide a large surface area and enhance the electrocatalytic activity of atacamite. At optimal conditions by differential pulse voltammetry (DPV), a good linear relationship was obtained between peak currents and GA concentrations in a wild linear range of 500 nM to 1 mM. Subsequently, the proposed sensor was used to detect GA in red wine as well as in green and black tea, confirming its great potential as a reliable alternative to conventional methods for GA determination.
摘要：
没食子酸（GA）是最重要的多酚之一，在食品中被广泛使用，化妆品,和制药工业由于其生物效应，如抗氧化剂，抗菌，抗癌，抗病毒，抗炎,和心脏保护特性。因此，简单,快,GA的灵敏测定尤为重要。考虑到GA是一种电活性化合物，电化学传感器由于其快速的响应时间，为GA定量提供了巨大的潜力，高灵敏度,和易用性。一个简单的，快,灵敏的GA传感器是在使用海绵作为天然3D聚合物的高性能生物纳米复合材料的基础上制造的，atacamite,和多壁碳纳米管(MWCNT)。由于3D多孔海绵和MWCNT的协同作用，开发的传感器对GA氧化表现出优异的响应，具有显着的电化学特征，它提供了大的表面积并增强了atacamite的电催化活性。在最佳条件下，通过差分脉冲伏安法（DPV），在500nM至1mM的野生线性范围内，峰值电流与GA浓度之间具有良好的线性关系。随后，所提出的传感器用于检测红葡萄酒以及绿茶和红茶中的GA，证实了其作为常规GA测定方法的可靠替代方法的巨大潜力。
