Abstract：
The incidence of psoriasis, an intractable long-lasting inflammatory skin disease, is increasing and has many complications and comorbidities. Approximately 14% of patients have psoriatic arthritis (PsA). Rheumatoid arthritis (RA) is not a rare disease worldwide, and some patients may have both PsA and RA. In the present study, we encountered seven patients with concurrent diagnoses of RA and psoriatic disease and reported the details of clinical data, treatment efficacy, and X-ray findings. The diagnosis may require not only classification criteria but also a comprehensive judgment in collaboration with rheumatology over time. In addition to methotrexate as an anchor drug, anti-tumor necrosis factor-α agents are the first choice of biological agents for treatment, and interleukin (IL)-17 inhibitors may be effective, as IL-17 is also involved in the pathogenesis of RA. When treating patients with both PsA and RA, it may be essential to consider the treatment strategy, depending on which disease is more active.
摘要：
牛皮癣的发病率，一种顽固性持久的炎症性皮肤病,正在增加，并有许多并发症和合并症。大约14%的患者患有银屑病关节炎(PsA)。类风湿性关节炎(RA)并不是世界范围内的罕见疾病,一些患者可能同时患有PsA和RA。在本研究中,我们遇到了7例同时诊断为RA和银屑病疾病的患者，并报告了详细的临床数据，治疗功效,和X光检查结果.随着时间的推移，诊断可能不仅需要分类标准，还需要与风湿病学合作的综合判断。除了甲氨蝶呤作为锚定药物,抗肿瘤坏死因子-α药物是治疗的首选生物制剂，白细胞介素（IL）-17抑制剂可能是有效的，IL-17也参与RA的发病机制。治疗同时患有PsA和RA的患者时，考虑治疗策略可能是至关重要的，取决于哪种疾病更活跃。
