Abstract：
In the field of phage applications and clinical treatment, virulent phages have been in the spotlight whereas temperate phages received, relatively speaking, less attention. The fact that temperate phages often carry virulent or drug-resistant genes is a constant concern and drawback in temperate phage applications. However, temperate phages also play a role in bacterial regulation. This review elucidates the biological properties of temperate phages based on their life cycle and introduces the latest work on temperate phage applications, such as on host virulence reduction, biofilm degradation, genetic engineering and phage display. The versatile use of temperate phages coupled with their inherent properties, such as economy, ready accessibility, wide variety and host specificity, make temperate phages a solid candidate in tackling bacterial infections.
摘要：
在噬菌体应用和临床治疗领域，有毒的噬菌体一直受到关注，而温带的噬菌体则受到关注，相对而言,少注意。温带噬菌体通常携带有毒或耐药基因的事实是温带噬菌体应用中的一个持续关注和缺点。然而,温带噬菌体也在细菌调节中发挥作用。这篇综述根据温带噬菌体的生命周期阐明了温带噬菌体的生物学特性，并介绍了温带噬菌体应用的最新工作，例如降低宿主毒力，生物膜降解，基因工程和噬菌体展示。温带噬菌体的广泛使用及其固有特性，比如经济，准备可访问性，多样性和宿主特异性，使温带噬菌体成为解决细菌感染的可靠候选者。
