Abstract：
Radiolucent anterior and posterior implants by carbon fiber-reinforced polyetheretherketone (CFR PEEK) aim to improve treatment of primary and secondary tumors of the spine during the last years. The aim of this study was to evaluate clinical and radiological outcomes after dorsoventral instrumentation using a CFR PEEK implant in a cohort of patients representing clinical reality.
A total of 25 patients with tumor manifestation of the thoracic and lumbar spine underwent vertebral body replacement (VBR) using an expandable CFR PEEK implant between January 2021 and January 2022. Patient outcome, complications, and radiographic follow-up were analyzed.
A consecutive series aged 65.8 ± 14.7 (27.6-91.2) years were treated at 37 vertebrae of tumor manifestation, including two cases (8.0%) of primary tumor as well as 23 cases (92.0%) of spinal metastases. Overall, 26 cages covering a median of 1 level (1-4) were implanted. Duration of surgery was 134 ± 104 (65-576) min, with a blood loss of 792 ± 785 (100-4000) ml. No intraoperative cage revision was required. Surgical complications were reported in three (12.0%) cases including hemothorax in two cases (one intraoperative, one postoperative) and atrophic wound healing disorder in one case. In two cases (8.0%), revision surgery was performed (fracture of the adjacent tumorous vertebrae, progressive construct failure regarding cage subsidence). No implant failure was observed.
VBR using CFR PEEK cages represents a legitimate surgical strategy which opens a variety of improvements-especially in patients in need of postoperative radiotherapy of the spine and MRI-based follow-up examinations.
A total of 25 patients with tumor manifestation of the thoracic and lumbar spine underwent vertebral body replacement (VBR) using an expandable CFR PEEK implant between January 2021 and January 2022. Patient outcome, complications, and radiographic follow-up were analyzed.
A consecutive series aged 65.8 ± 14.7 (27.6-91.2) years were treated at 37 vertebrae of tumor manifestation, including two cases (8.0%) of primary tumor as well as 23 cases (92.0%) of spinal metastases. Overall, 26 cages covering a median of 1 level (1-4) were implanted. Duration of surgery was 134 ± 104 (65-576) min, with a blood loss of 792 ± 785 (100-4000) ml. No intraoperative cage revision was required. Surgical complications were reported in three (12.0%) cases including hemothorax in two cases (one intraoperative, one postoperative) and atrophic wound healing disorder in one case. In two cases (8.0%), revision surgery was performed (fracture of the adjacent tumorous vertebrae, progressive construct failure regarding cage subsidence). No implant failure was observed.
VBR using CFR PEEK cages represents a legitimate surgical strategy which opens a variety of improvements-especially in patients in need of postoperative radiotherapy of the spine and MRI-based follow-up examinations.
摘要：
目的：碳纤维增强聚醚醚酮（CFRPEEK）的射线可透的前后植入物旨在改善最近几年对脊柱原发性和继发性肿瘤的治疗。这项研究的目的是在代表临床现实的一组患者中使用CFRPEEK植入物评估背腹侧器械后的临床和放射学结果。
方法：在2021年1月至2022年1月期间，共有25例表现为胸腰椎肿瘤的患者使用可扩张的CFRPEEK植入物进行椎体置换（VBR）。患者结果,并发症,和影像学随访进行了分析。
结果：对年龄为65.8±14.7（27.6-91.2）岁的37个椎体的肿瘤表现进行了连续系列治疗，其中原发肿瘤2例(8.0%),脊柱转移瘤23例(92.0%)。总的来说,植入26个笼子，中位数为1级（1-4）。手术时间134±104(65-576)min,失血量为792±785（100-4000）ml。术中不需要进行笼子翻修。手术并发症3例（12.0%），其中血胸2例（1例术中，术后1例）和萎缩性伤口愈合障碍。在两种情况下（8.0％），进行了翻修手术（邻近肿瘤椎骨的骨折，关于网箱沉降的渐进结构破坏)。没有观察到植入物失败。
结论：使用CFRPEEK笼的VBR代表了一种合法的手术策略，可以改善多种情况，尤其是在需要脊柱术后放疗和基于MRI的随访检查的患者中。
方法：在2021年1月至2022年1月期间，共有25例表现为胸腰椎肿瘤的患者使用可扩张的CFRPEEK植入物进行椎体置换（VBR）。
结果：对年龄为65.8±14.7（27.6-91.2）岁的37个椎体的肿瘤表现进行了连续系列治疗，
结论：使用CFRPEEK笼的VBR代表了一种合法的手术策略，可以改善多种情况，尤其是在需要脊柱术后放疗和基于MRI的随访检查的患者中。
