PDF(Pubmed)
Abstract：
UNASSIGNED: To assess postoperative oral morbidity through meta-analysis of comparative studies for closure or non-closure of the buccal mucosa graft harvest area in patients undergoing urethroplasty.
UNASSIGNED: A systematic literature review was conducted in January 2022. Randomized controlled studies were assessed according to the Cochrane collaboration guidelines. Postoperative pain, difficult mouth opening, alteration of oral salivation, perioral numbness, and tolerance of solid and liquid intake results were assessed. Standard mean differences and risk ratios with 95% confidence intervals were estimated for relative risk. Assessment was performed with subgroup analyses according to time points.
UNASSIGNED: This meta-analysis included 373 patients in 7 randomized studies. The oral pain overall pooled effect estimates were investigated for the time points of day 0-1, day 3-7 and months 1-6. According to corrected effect estimates after sensitivity analysis, at the day 0-1 time point, the non-closure group was significantly superior compared to the closure group. But there was no difference at the other time points and in total. The overall pooled effect estimates for difficult mouth opening were investigated at 4 time points (day 1, days 5-7, months 1-3 and months 6). After sensitivity analysis, the overall pooled effect estimates at 6 months were significantly superior for the non-closure group. There were no significant differences between the non-closed and closed groups based on the overall pooled-effect estimates for oral numbness, salivary secretion alteration, and tolerance of liquid and solid food variants.
UNASSIGNED: The non-closure group was more advantageous in terms of oral pain in the early postoperative period. There were no differences between the groups in terms of alteration of salivation, oral numbness and toleration of liquid/solid food. Although the non-closed group seems more advantageous in terms of ease in mouth movements, more studies are needed to prove this.
UNASSIGNED: A systematic literature review was conducted in January 2022. Randomized controlled studies were assessed according to the Cochrane collaboration guidelines. Postoperative pain, difficult mouth opening, alteration of oral salivation, perioral numbness, and tolerance of solid and liquid intake results were assessed. Standard mean differences and risk ratios with 95% confidence intervals were estimated for relative risk. Assessment was performed with subgroup analyses according to time points.
UNASSIGNED: This meta-analysis included 373 patients in 7 randomized studies. The oral pain overall pooled effect estimates were investigated for the time points of day 0-1, day 3-7 and months 1-6. According to corrected effect estimates after sensitivity analysis, at the day 0-1 time point, the non-closure group was significantly superior compared to the closure group. But there was no difference at the other time points and in total. The overall pooled effect estimates for difficult mouth opening were investigated at 4 time points (day 1, days 5-7, months 1-3 and months 6). After sensitivity analysis, the overall pooled effect estimates at 6 months were significantly superior for the non-closure group. There were no significant differences between the non-closed and closed groups based on the overall pooled-effect estimates for oral numbness, salivary secretion alteration, and tolerance of liquid and solid food variants.
UNASSIGNED: The non-closure group was more advantageous in terms of oral pain in the early postoperative period. There were no differences between the groups in terms of alteration of salivation, oral numbness and toleration of liquid/solid food. Although the non-closed group seems more advantageous in terms of ease in mouth movements, more studies are needed to prove this.
摘要：
UNASSIGNED：通过对尿道成形术患者颊粘膜移植物收获区闭合或不闭合的比较研究的荟萃分析，评估术后口腔发病率。
UNASSIGNED：2022年1月进行了系统的文献综述。根据Cochrane协作指南对随机对照研究进行评估。术后疼痛,难以张开嘴，口腔唾液分泌改变，口周麻木,并评估了固体和液体摄入结果的耐受性。估计相对风险的标准平均差和95%置信区间的风险比。根据时间点进行亚组分析评估。
UNASSIGNED：这项荟萃分析纳入了7项随机研究中的373名患者。在第0-1天、第3-7天和第1-6个月的时间点研究口腔疼痛总体汇集效应估计。根据敏感性分析后的校正效果估计，在第0-1天的时间点，非闭合组明显优于闭合组.但是在其他时间点和总体上没有差异。在4个时间点(第1天、第5-7天、第1-3个月和第6个月)调查难以张口的总体汇集效应估计。经过敏感性分析，非封闭组6个月时的总体汇总效应估计值显著优于对照组.根据口腔麻木的总体汇总效应估计，非封闭组和封闭组之间没有显着差异，唾液分泌改变，以及对液体和固体食物变体的耐受性。
UNASSIGNED：非封闭组在术后早期口腔疼痛方面更有利。两组之间在流涎改变方面没有差异，口腔麻木和液体/固体食物的耐受性。尽管非封闭组似乎在易于口腔运动方面更有利，需要更多的研究来证明这一点。
UNASSIGNED：2022年1月进行了系统的文献综述。
UNASSIGNED：这项荟萃分析纳入了7项随机研究中的373名患者。
UNASSIGNED：非封闭组在术后早期口腔疼痛方面更有利。
