Abstract：
Chiral self-sorting during the formation of cage-like molecules continues to fascinate and advance our understanding of the phenomenon in general. Herein, we report the chiral self-sorting in the Pd6 L12 -type metal-organic cages. When a racemic mixture of axially chiral bis-pyridyl ligands undergo coordination-driven self-assembly with Pd(II) ions to form Pd6 L12 -type cages, the system has the option of chiral self-sorting to afford any of at least 70 pairs of (one homochiral and 69 heterochiral) enantiomers and 5 meso isomers or a statistical mixture of everything. However, the system resulted in diastereoselective self-assembly through a high-fidelity chiral social self-sorting to form a racemic mixture of D3 symmetric heterochiral [Pd6 (L6R/6S )12 ]12+ /[Pd6 (L6S/6R )12 ]12+ cages.
摘要：
在笼状分子形成过程中的手性自分选继续吸引并促进我们对该现象的总体理解。在这里，我们报道了Pd6L12型金属有机笼中的手性自分选。当轴向手性双吡啶基配体的外消旋混合物与Pd（II）离子进行配位驱动的自组装以形成Pd6L12型笼时，该系统具有手性自分选的选项，以提供至少70对（一个同手性和69杂手性）对映异构体和5个内消旋异构体或所有物质的统计混合物。然而,该系统通过高保真手性社会自分类导致非对映选择性自组装，形成D3对称异手性[Pd6L6R/6S12]12+/[Pd6L6S/6R12]12+笼的外消旋混合物。
