Abstract：
To establish consensus definitions for necrotising otitis externa (NOE) to facilitate the diagnosis and exclusion of NOE in clinical practice and expedite future high-quality study of this neglected condition.
The work comprised of a systematic review of the literature, five iterative rounds of consultation via a Delphi process and open discussion within the collaborative. An expert panel analysed the results to produce the final outputs which were shared with and endorsed by national specialty bodies.
Secondary care in the UK.
UK clinical specialists practising in infection, ear nose and throat (ENT) surgery or radiology.
Definitions and statements meeting the following criteria were accepted: (a) minimum of 70% of respondents in agreement or strong agreement with a definition/statement AND (b) <15% of respondents in disagreement or strong disagreement with a definition/statement.
Seventy-four UK clinicians specialising in ENT, Infection and Radiology with a special interest in NOE took part in the work which was undertaken between 2019 and 2021. The minimum response rate for a Round was 76%. Consensus criteria for all proposed case definitions, outcome definitions and consensus statements were met in the fifth round.
This work distills the clinical opinion of a large group of multidisciplinary specialists from across the UK to create practical definitions and statements to support clinical practice and research for NOE. This is the first step in an iterative process. Further work will seek to validate and test these definitions and inform their evolution.
The work comprised of a systematic review of the literature, five iterative rounds of consultation via a Delphi process and open discussion within the collaborative. An expert panel analysed the results to produce the final outputs which were shared with and endorsed by national specialty bodies.
Secondary care in the UK.
UK clinical specialists practising in infection, ear nose and throat (ENT) surgery or radiology.
Definitions and statements meeting the following criteria were accepted: (a) minimum of 70% of respondents in agreement or strong agreement with a definition/statement AND (b) <15% of respondents in disagreement or strong disagreement with a definition/statement.
Seventy-four UK clinicians specialising in ENT, Infection and Radiology with a special interest in NOE took part in the work which was undertaken between 2019 and 2021. The minimum response rate for a Round was 76%. Consensus criteria for all proposed case definitions, outcome definitions and consensus statements were met in the fifth round.
This work distills the clinical opinion of a large group of multidisciplinary specialists from across the UK to create practical definitions and statements to support clinical practice and research for NOE. This is the first step in an iterative process. Further work will seek to validate and test these definitions and inform their evolution.
摘要：
目的：建立坏死性外耳炎（NOE）的共识定义，以促进临床实践中NOE的诊断和排除，并加快未来对这种被忽视情况的高质量研究。
方法：这项工作包括对文献的系统回顾，五轮迭代协商经由过程Delphi和内部协作睁开研讨。一个专家小组对结果进行了分析，以产生最终产出，并与国家专业机构共享并得到其认可。
方法：英国的二级保健。
方法：英国感染临床专家，耳鼻喉（ENT）手术或放射学。
方法：符合以下标准的定义和陈述被接受：(a)至少70%的受访者同意或强烈同意定义/陈述，以及(b)<15%的受访者不同意或强烈不同意定义/陈述。
结果：74名专门从事耳鼻喉科的英国临床医生，对NOE特别感兴趣的感染和放射学参与了2019年至2021年之间进行的工作。一轮的最低反应率为76%。所有拟议案例定义的共识标准，在第五轮中达成了结果定义和共识声明.
结论：这项工作提炼出来自英国各地的一大批多学科专家的临床意见，以创建实用的定义和声明，以支持NOE的临床实践和研究。这是迭代过程的第一步。进一步的工作将寻求验证和测试这些定义并告知其演变。
方法：这项工作包括对文献的系统回顾，
方法：英国的二级保健。
方法：英国感染临床专家，
方法：符合以下标准的定义和陈述被接受：(a)至少70%的受访者同意或强烈同意定义/陈述，以及(b)<15%的受访者不同意或强烈不同意定义/陈述。
结果：74名专门从事耳鼻喉科的英国临床医生，
结论：这项工作提炼出来自英国各地的一大批多学科专家的临床意见，以创建实用的定义和声明，以支持NOE的临床实践和研究。
