Abstract:
The role of nutrition is increasingly recognized in the management of chronic immune diseases. However, the role of an immune-supportive diet as adjuvant therapy in the management of allergic disease has not been similarly explored. This review assesses the existing evidence for a relationship between nutrition, immune function, and allergic disease from a clinical perspective. In addition, the authors propose an immune-supportive diet to enhance dietary interventions and complementing other therapeutic options for allergic disease from early life to adulthood. A narrative review of the literature was conducted, to determine the evidence of the relationship between nutrition and immune function, overall health, epithelial barrier function, and gut microbiome, particularly in relation to allergy. Studies on food supplements were excluded. The evidence was assessed and utilized to develop a sustainable immune-supportive diet to complement other therapies in allergic disease. The proposed diet consists of a highly diverse range of fresh, whole, and minimally processed plant-based and fermented foods supplemented with moderate amounts of nuts, omega-3-rich foods and animal-based products in proportional amounts of the EAT-Lancet diet, such as (fatty) fish, (fermented) milk products which may be full-fat and eggs, lean meat or poultry, which may be free-range or organic.
摘要:
营养在慢性免疫疾病的管理中的作用日益得到认可。然而,免疫支持饮食在过敏性疾病治疗中作为辅助治疗的作用尚未得到类似的研究.这篇综述评估了营养与营养之间关系的现有证据,免疫功能,从临床角度看过敏性疾病.此外,作者提出了一种免疫支持饮食,以加强饮食干预,并补充过敏性疾病从早期到成年的其他治疗选择.对文献进行了叙述性回顾,为了确定营养和免疫功能之间关系的证据,整体健康,上皮屏障功能,和肠道微生物组,特别是与过敏有关。对食品补充剂的研究被排除在外。评估并利用证据来开发可持续的免疫支持饮食,以补充过敏性疾病的其他疗法。拟议的饮食包括高度多样化的新鲜,整体和最低限度加工的植物性和发酵食品,补充适量的坚果,富含omega-3的食物和动物性产品,与EAT-Lancet饮食成比例,如(脂肪)鱼,(发酵)奶制品,可能是全脂和鸡蛋,瘦肉或家禽,这可能是自由范围或有机。