PDF(Pubmed)
Abstract：
We report a straightforward method for creating large-area, microscale resolution patterns of functional amines on self-assembled monolayers by the photoinduced local acidification of a flat elastomeric stamp enriched with photoacid. The limited diffusivity of the photoactivated merocyanine acid in poly(dimethylsiloxane) (PDMS) enabled to confine efficient deprotection of N-tert-butyloxycarbonyl amino group (N-Boc) to line widths below 10 μm. The experimental setup is very simple and is built around the conventional HD-DVD optical pickup. The method allows cost-efficient, maskless, large-area chemical patterning while avoiding potentially cytotoxic photochemical reaction products. The activation of the embedded photoacid occurs within the stamp upon illumination with the laser beam and the process is fully reversible. Preliminary positive results highlight the possibility of repeatable use of the same stamp for the creation of different patterns.
摘要：
我们报告了一种创建大面积的简单方法，通过光诱导富含光酸的扁平弹性体印模的局部酸化，在自组装单层上官能胺的微观分辨率模式。光活化的部花青酸在聚（二甲基硅氧烷）（PDMS）中的有限扩散系数能够将N-叔丁氧基羰基氨基（N-Boc）的有效脱保护限制在10μm以下的线宽。实验设置非常简单，并且围绕常规的HD-DVD光学拾取器构建。该方法具有成本效益，无面罩,大面积化学图案化，同时避免潜在的细胞毒性光化学反应产物。在用激光束照射时,嵌入的光酸的激活发生在印模内,并且该过程是完全可逆的。初步的积极结果强调了可重复使用相同图章来创建不同图案的可能性。
