Removal of Polymer Clips From the Gallbladder Fossa in a Patient With Ehlers-Danlos Syndrome (EDS) to Treat Mast Cell Activation Syndrome (MCAS): A Case Report.

从 Ehlers - Danlos 综合征 （ EDS ） 患者的胆囊窝中去除聚合物夹治疗肥大细胞活化综合征 （ MCAS ） ： 病例报告。

• 发表时间: Jan 2023
• 来源期刊: Cureus
• DOI: 10.7759/cureus.33704
• PMID: 36788923
• 文章类型: Case Reports
• 作者列表: Xiao Y,Calixte DA,Fry E,Tiesenga F

关键词: ehlers-danlos syndrome; foreign body removal; hypersensitive reaction; mast cell activation syndrome; noninvasive surgery

Abstract

Ehlers-Danlos syndrome (EDS) is a group of hereditary disorders characterized by fragility of connective tissue. Clinical manifestations of the disorder involve the skin, joints, blood vessels, and other internal organs. We report the case of a 29-year-old female suffering from EDS and mast cell activation syndrome (MCAS). Her history includes multiple orthopedic surgeries leading to the worsening of her symptoms. This was determined to be due to medical implants placed during her multiple procedures predisposing her to severe immunological reactions. This case report emphasizes the importance of meticulous surgical intervention when managing patients with EDS.

摘要

Ehlers-Danlos综合征（EDS）是一组以结缔组织脆性为特征的遗传性疾病。该疾病的临床表现涉及皮肤，接头,血管,和其他内脏。我们报告了一名29岁女性患有EDS和肥大细胞活化综合征（MCAS）的病例。她的病史包括多次骨科手术，导致症状恶化。这被确定是由于在她的多次手术期间放置的医疗植入物使她容易发生严重的免疫反应。此病例报告强调了在管理EDS患者时进行细致手术干预的重要性。