PDF(Pubmed)
Abstract：
UNASSIGNED: Aplasia of the salivary glands, either partial or involving all the major and possibly the minor salivary glands, is a very rare cause of hyposalivation. The aim of this case report is to present a case of aplasia of the major and minor salivary glands and discuss the relevant literature.
UNASSIGNED: A 23-year-old woman, with a non-contributory medical and family history was referred due to rampant caries, that could not be attributed to any obvious aetiology. No sicca symptoms, previous parotid gland swelling or general symptoms were reported. Clinically, oral mucosa dryness and extended dental erosions and caries were observed, while the orifices of the excretory ducts of the parotid and submandibular salivary glands were not evident. Unstimulated and stimulated saliva flow rates were severely diminished, while a diagnostic biopsy of the lower lip revealed absence of minor salivary glands. Detailed hematologic and immunological investigations to exclude systemic disorders were also within normal limits. Ultrasound and magnetic resonance imaging revealed the absence of all major salivary glands, confirming the clinical diagnosis of congenital aplasia of the salivary glands.
UNASSIGNED: Oral hygiene instructions and dietary advice were given while dental products with fluoride and saliva substitutes were administered and appropriate dental treatment was implemented. Regular dental follow-up was also advised.
UNASSIGNED: Timely diagnosis of aplasia of the salivary glands is important, considering the detrimental effects of the absence of saliva on oral health. Management consists of the use of saliva substitutes, nutritional adaptation, maintenance of oral health and regular dental follow-ups.
UNASSIGNED: A 23-year-old woman, with a non-contributory medical and family history was referred due to rampant caries, that could not be attributed to any obvious aetiology. No sicca symptoms, previous parotid gland swelling or general symptoms were reported. Clinically, oral mucosa dryness and extended dental erosions and caries were observed, while the orifices of the excretory ducts of the parotid and submandibular salivary glands were not evident. Unstimulated and stimulated saliva flow rates were severely diminished, while a diagnostic biopsy of the lower lip revealed absence of minor salivary glands. Detailed hematologic and immunological investigations to exclude systemic disorders were also within normal limits. Ultrasound and magnetic resonance imaging revealed the absence of all major salivary glands, confirming the clinical diagnosis of congenital aplasia of the salivary glands.
UNASSIGNED: Oral hygiene instructions and dietary advice were given while dental products with fluoride and saliva substitutes were administered and appropriate dental treatment was implemented. Regular dental follow-up was also advised.
UNASSIGNED: Timely diagnosis of aplasia of the salivary glands is important, considering the detrimental effects of the absence of saliva on oral health. Management consists of the use of saliva substitutes, nutritional adaptation, maintenance of oral health and regular dental follow-ups.
摘要：
未经批准：唾液腺发育不全，部分或涉及所有主要和可能的次要唾液腺，是一个非常罕见的原因。此病例报告的目的是介绍一例主要和次要唾液腺发育不全的病例，并讨论相关文献。
未经授权：一个23岁的女人，由于龋齿猖獗，患者有非缴费型病史和家族史，这不能归因于任何明显的病因。没有干燥症状,曾报告腮腺肿胀或一般症状.临床上,观察到口腔粘膜干燥，牙齿糜烂和龋齿，而腮腺和颌下腺的排泄管口不明显。未刺激和受刺激的唾液流速严重下降，而下唇的诊断性活检显示缺少少量唾液腺。详细的血液学和免疫学检查以排除全身性疾病也在正常范围内。超声和磁共振成像显示所有主要唾液腺的缺失，确认唾液腺先天性发育不全的临床诊断。
UNASSIGNED：给予口腔卫生指导和饮食建议，同时给予含有氟化物和唾液替代品的牙科产品，并实施适当的牙科治疗。还建议定期进行牙科随访。
未经证实：及时诊断唾液腺发育不全很重要，考虑到唾液缺乏对口腔健康的有害影响。管理包括使用唾液替代品，营养适应，维护口腔健康和定期牙科随访。
未经授权：一个23岁的女人，
UNASSIGNED：给予口腔卫生指导和饮食建议，同时给予含有氟化物和唾液替代品的牙科产品，并实施适当的牙科治疗。
未经证实：及时诊断唾液腺发育不全很重要，
