PDF(Pubmed)
Abstract：
UNASSIGNED: To determine the effectiveness of transcranial magnetic stimulation in improving cerebellar ataxia.
UNASSIGNED: PubMed, EMBASE, the Cochrane Library, Springer, Science Direct, the China National Knowledge Infrastructure (CNKI) and the China Science and Technology Journal Database (VIP) were searched until 2022.
UNASSIGNED: Trials with transcranial magnetic stimulation on the effects on cerebellar ataxia were included, and the effect size was evaluated using the standardized mean difference (SMD) or mean difference (MD) and a 95% confidence interval (CI).
UNASSIGNED: Eight studies comprising 272 participants, published between 2014 and 2022, were included. The results revealed that the effect of TMS on patients with cerebellar ataxia as assessed by the International Cooperative Ataxia Rating Scale (ICRAS), the Scale for the Assessment and Rating of Ataxia (SARA), the Berg Balance Scale (BBS), and the Timed Up and Go (TUG) test was statistically significant (P < 0.01) with low heterogeneity among the studies (I2 = 4, 27, 0, and 0% respectively).
UNASSIGNED: The effects of transcranial magnetic stimulation in improving cerebellar ataxia in the affected patients are significant. TMS targeting the cerebellar structures can induce changes in the excitability of the cerebellar-thalamus-cortical pathways; thus, it is necessary to carry out large-scale research with good design and high quality in the future.
UNASSIGNED: PubMed, EMBASE, the Cochrane Library, Springer, Science Direct, the China National Knowledge Infrastructure (CNKI) and the China Science and Technology Journal Database (VIP) were searched until 2022.
UNASSIGNED: Trials with transcranial magnetic stimulation on the effects on cerebellar ataxia were included, and the effect size was evaluated using the standardized mean difference (SMD) or mean difference (MD) and a 95% confidence interval (CI).
UNASSIGNED: Eight studies comprising 272 participants, published between 2014 and 2022, were included. The results revealed that the effect of TMS on patients with cerebellar ataxia as assessed by the International Cooperative Ataxia Rating Scale (ICRAS), the Scale for the Assessment and Rating of Ataxia (SARA), the Berg Balance Scale (BBS), and the Timed Up and Go (TUG) test was statistically significant (P < 0.01) with low heterogeneity among the studies (I2 = 4, 27, 0, and 0% respectively).
UNASSIGNED: The effects of transcranial magnetic stimulation in improving cerebellar ataxia in the affected patients are significant. TMS targeting the cerebellar structures can induce changes in the excitability of the cerebellar-thalamus-cortical pathways; thus, it is necessary to carry out large-scale research with good design and high quality in the future.
摘要：
UNASSIGNED：确定经颅磁刺激改善小脑共济失调的有效性。
未经授权：PubMed，EMBASE,Cochrane图书馆,Springer,科学直接，中国国家知识基础设施（CNKI）和中国科技期刊数据库（VIP）检索至2022年。
UNASSIGNED：包括经颅磁刺激对小脑共济失调影响的试验，并使用标准化平均差(SMD)或平均差(MD)和95%置信区间(CI)评估效应大小。
未经评估：由272名参与者组成的8项研究，2014年至2022年期间出版的，包括在内。结果表明，通过国际合作共济失调评定量表（ICRAS）评估，TMS对小脑共济失调患者的影响，共济失调评估和评级量表(SARA)，伯格平衡量表(BBS)，且TimedUp和Go(TUG)检验有统计学意义(P<0.01),研究间异质性较低(I2分别为4、27、0和0%)。
UNASSIGNED：经颅磁刺激改善患者小脑共济失调的效果是显著的。针对小脑结构的TMS可以诱导小脑-丘脑-皮质通路的兴奋性变化；因此，未来有必要开展设计好、质量高的大规模研究。
未经授权：PubMed，
UNASSIGNED：包括经颅磁刺激对小脑共济失调影响的试验，
未经评估：由272名参与者组成的8项研究，
UNASSIGNED：经颅磁刺激改善患者小脑共济失调的效果是显著的。
