PDF(Pubmed)
Abstract：
UNASSIGNED: Knowledge regarding the modifiable risk factors of dementia is fundamental to guide public health policy. We aimed to estimate the population attributable fraction of modifiable risk factors of dementia among adults from a nationwide epidemiological study.
UNASSIGNED: We used the public database of the Brazilian Longitudinal Study of Aging (ELSI-Brazil) to calculate the Population Attributable Fraction (PAF) for ten risk factors, including education level, hearing loss, hypertension, alcohol consumption, obesity, active smoking, depression, social isolation, physical inactivity, and diabetes. PAF was estimated for this sample after accounting for the communality of each risk factor.
UNASSIGNED: The ten preventable risk factors for dementia accounted for 50·5% of the Population Attributable Fraction in Brazil. Hearing loss (14·2%), physical inactivity (11·2%), and hypertension (10·4%) accounted for the highest PAF among all the risk factors. Considerable variation in the relative contribution of the different risk factors was found in different regions.
UNASSIGNED: This study might provide an opportunity to change the impact of dementia in Brazil. By targeting modifiable risk factors of dementia, the health of individuals in Brazil might be considerably improved.
UNASSIGNED: This study did not receive any funding.
UNASSIGNED: We used the public database of the Brazilian Longitudinal Study of Aging (ELSI-Brazil) to calculate the Population Attributable Fraction (PAF) for ten risk factors, including education level, hearing loss, hypertension, alcohol consumption, obesity, active smoking, depression, social isolation, physical inactivity, and diabetes. PAF was estimated for this sample after accounting for the communality of each risk factor.
UNASSIGNED: The ten preventable risk factors for dementia accounted for 50·5% of the Population Attributable Fraction in Brazil. Hearing loss (14·2%), physical inactivity (11·2%), and hypertension (10·4%) accounted for the highest PAF among all the risk factors. Considerable variation in the relative contribution of the different risk factors was found in different regions.
UNASSIGNED: This study might provide an opportunity to change the impact of dementia in Brazil. By targeting modifiable risk factors of dementia, the health of individuals in Brazil might be considerably improved.
UNASSIGNED: This study did not receive any funding.
摘要：
UNASSIGNED：关于痴呆的可改变危险因素的知识是指导公共卫生政策的基础。我们旨在从全国流行病学研究中估计成年人中痴呆的可改变危险因素的人群归因比例。
UNASSIGNED：我们使用巴西老龄化纵向研究（ELSI-Brazil）的公共数据库来计算十个危险因素的人口归因分数（PAF），包括教育水平，听力损失,高血压,酒精消费,肥胖，积极吸烟,抑郁症,社会孤立,缺乏身体活动，和糖尿病。在考虑了每个风险因素的公共性后，对该样本的PAF进行了估计。
UNASSIGNED：痴呆症的十种可预防的危险因素占巴西人口归因比例的50·5％。听力损失（14·2%），缺乏身体活动（11·2%），在所有危险因素中，高血压(10·4%)占最高的PAF。在不同地区，不同危险因素的相对贡献存在相当大的差异。
未经评估：这项研究可能为改变巴西痴呆症的影响提供了机会。通过针对可改变的痴呆危险因素，巴西个人的健康状况可能会有很大改善。
未经评估：本研究未获得任何资助。
UNASSIGNED：我们使用巴西老龄化纵向研究（ELSI-Brazil）的公共数据库来计算十个危险因素的人口归因分数（PAF），
UNASSIGNED：痴呆症的十种可预防的危险因素占巴西人口归因比例的50·5％。
未经评估：这项研究可能为改变巴西痴呆症的影响提供了机会。
未经评估：本研究未获得任何资助。
