PDF(Pubmed)
Abstract：
UNASSIGNED: Carcasses from animal experiments with RG-3 pathogens should be decontaminated onsite in Austria.
UNASSIGNED: The aim of this study was to find out if the use of pass-through autoclaves for the decontamination of animal carcasses (up to 40 kg of weight) could serve as a routine method for smaller laboratories, as the installation of special carcass decontamination plants may be cost prohibitive.
UNASSIGNED: Biological indicators (BIs) were implanted into the carcasses of animals of different sizes and species with a novel method using stainless steel pipes. The bodies were placed in autoclavable plastic bags and equipped with thermal probes by insertion through the rectum. Subsequently a factory default autoclave cycle for liquids was performed, which holds a core temperature of 121°C for 20 min.
UNASSIGNED: The weight of the carcasses ranged from 1 to 42 kg, the duration of the individual cycles reached from 2.2 to 17.23 h. Decontamination was successful every single time as shown by the BIs. The application through the natural orifices with the help of the application tools seems to offer a reliable alternative for implanting the BIs into the carcasses without creating new openings. Insulation properties did not pose substantial challenges to the process. Limitations on the packaging procedure were identified in carcasses larger than 30 kg.
UNASSIGNED: Based on the results of this study, using pass-through autoclaves represents an option as a routine method for the decontamination of animal carcasses up to at least 40 kg.
UNASSIGNED: The aim of this study was to find out if the use of pass-through autoclaves for the decontamination of animal carcasses (up to 40 kg of weight) could serve as a routine method for smaller laboratories, as the installation of special carcass decontamination plants may be cost prohibitive.
UNASSIGNED: Biological indicators (BIs) were implanted into the carcasses of animals of different sizes and species with a novel method using stainless steel pipes. The bodies were placed in autoclavable plastic bags and equipped with thermal probes by insertion through the rectum. Subsequently a factory default autoclave cycle for liquids was performed, which holds a core temperature of 121°C for 20 min.
UNASSIGNED: The weight of the carcasses ranged from 1 to 42 kg, the duration of the individual cycles reached from 2.2 to 17.23 h. Decontamination was successful every single time as shown by the BIs. The application through the natural orifices with the help of the application tools seems to offer a reliable alternative for implanting the BIs into the carcasses without creating new openings. Insulation properties did not pose substantial challenges to the process. Limitations on the packaging procedure were identified in carcasses larger than 30 kg.
UNASSIGNED: Based on the results of this study, using pass-through autoclaves represents an option as a routine method for the decontamination of animal carcasses up to at least 40 kg.
摘要：
未经批准：用RG-3病原体进行动物实验的尸体应在奥地利现场净化。
UNASSIGNED：这项研究的目的是找出使用穿透式高压灭菌器对动物尸体（重量不超过40公斤）进行净化是否可以作为较小的常规方法实验室，因为安装特殊的car体净化设备可能成本过高。
UNASSIGNED：使用不锈钢管的新颖方法将生物指示剂（BIs）植入不同大小和种类的动物的尸体中。将身体放置在可高压灭菌的塑料袋中，并通过直肠插入配备热探针。随后，进行了工厂默认的液体高压釜循环，其保持121°C的核心温度20分钟。
未经评估：屠体的重量为1至42公斤，单个周期的持续时间从2.2到17.23小时。如BI所示，每一次净化都是成功的。在应用工具的帮助下通过自然孔口的应用似乎提供了将BI植入到屠体中而不产生新开口的可靠替代方案。绝缘性能并未对该过程构成实质性挑战。在大于30kg的屠体中确定了对包装程序的限制。
UNASSIGNED：根据这项研究的结果，使用穿透式高压灭菌器代表了一种用于净化至少40公斤动物尸体的常规方法。
UNASSIGNED：这项研究的目的是找出使用穿透式高压灭菌器对动物尸体（重量不超过40公斤）进行净化是否可以作为较小的常规方法实验室，因为安装特殊的car体净化设备可能成本过高。
UNASSIGNED：使用不锈钢管的新颖方法将生物指示剂（BIs）植入不同大小和种类的动物的尸体中。将身体放置在可高压灭菌的塑料袋中，并通过直肠插入配备热探针。随后，进行了工厂默认的液体高压釜循环，其保持121°C的核心温度20分钟。
未经评估：屠体的重量为1至42公斤，单个周期的持续时间从2.2到17.23小时。如BI所示，每一次净化都是成功的。在应用工具的帮助下通过自然孔口的应用似乎提供了将BI植入到屠体中而不产生新开口的可靠替代方案。绝缘性能并未对该过程构成实质性挑战。在大于30kg的屠体中确定了对包装程序的限制。
UNASSIGNED：根据这项研究的结果，使用穿透式高压灭菌器代表了一种用于净化至少40公斤动物尸体的常规方法。
