PDF(Pubmed)
Abstract：
Herpes zoster ophthalmicus (HZO) is a rare presentation of herpes zoster in children; however, it may become chronic and debilitating. The pathophysiology of HZO complications is not completely understood and may include virus virulence, vascular and neural inflammation and immune reactivity. Therefore, clinical experts suggest an antiviral agent combined with topical steroids, but treatment duration and the need for secondary prophylaxis, given the likelihood of recurrence, are not clearly defined. We present a complex case of HZO in a varicella zoster virus (VZV)-vaccinated toddler successfully treated with acyclovir and topical steroids. We also present a review of the relevant literature regarding the therapeutic management and long-term sequelae of HZO in children.
摘要：
眼带状疱疹（HZO）是儿童带状疱疹的罕见表现；然而，它可能会变得慢性和衰弱。HZO并发症的病理生理学尚未完全了解，可能包括病毒毒力，血管和神经炎症和免疫反应性。因此,临床专家建议抗病毒药物结合局部类固醇，但是治疗持续时间和二级预防的需要，考虑到复发的可能性，没有明确定义。我们介绍了一例水痘带状疱疹病毒（VZV）接种疫苗的幼儿中HZO的复杂病例，该幼儿成功地用阿昔洛韦和局部类固醇治疗。我们还对儿童HZO的治疗管理和长期后遗症的相关文献进行了综述。
