关键词: Ablative fractional laser Ablative laser Acne Atrophic scar Burn scar CO2 laser Er-YAG laser Erbium YAG laser Fractional laser Hypertrophic scar Laser Meso-needling Micro-needling Needling RF-needling Scar Striae Systematic review

Mesh : Humans Acne Vulgaris Atrophy / pathology Carbon Dioxide Cicatrix / pathology Cicatrix, Hypertrophic / pathology Erbium Lasers, Gas / therapeutic use Lasers, Solid-State / therapeutic use Prospective Studies Randomized Controlled Trials as Topic Skin / pathology Treatment Outcome Clinical Trials as Topic

来  源:   DOI:10.1007/s10103-022-03694-x

Abstract:
The aim of this study is to compare needling (RF-needling, meso-needling, micro-needling) and ablative fractional lasers (CO2, erbium-YAG) in the treatment of atrophic and hypertrophic scars in a systematic review. The database was searched, and 10 articles were selected that were relevant in terms of content, topic, and purpose and met the inclusion criteria. Of all the articles reviewed in this study, there were 2 randomized split-face trials (20%), 1 controlled nonrandomized trial (10%), 1 controlled randomized phase III clinical trial (10%), 1 prospective trial (10%), 1 prospective nonrandomized open-label trial (10%), and 1 randomized comparative trial (10%), with the type of study not reported in 3 articles. We used Endnote X8 to review the articles and extract data. After review, the studies were analyzed and categorized. No statistically significant difference was found between the two methods, laser and micro-needling, in the treatment of atrophic and hypertrophic scars in 60% of the articles studied, and both showed significant improvement (70% or more improvement to complete response). Significant improvement was noted in 20% of the studies reviewed for the laser and micro-needling treatment methods. The results of this study show that needling and ablative fractional lasers are tolerable and safe procedures with no significant difference in the treatment of skin scars in sixty percent of the studies.
摘要:
这项研究的目的是比较针刺(射频针刺,介观针刺,微针刺)和烧蚀分数激光(CO2,铒-YAG)治疗萎缩性和肥厚性瘢痕的系统评价。对数据库进行了搜索,选择了10篇内容相关的文章,topic,和目的,并符合纳入标准。在这项研究中回顾的所有文章中,有2项随机分面试验(20%),1项对照非随机对照试验(10%),1项随机对照III期临床试验(10%),1个前瞻性试验(10%),1项前瞻性非随机开放标签试验(10%),和1项随机比较试验(10%),研究类型未在3篇文章中报道。我们使用EndnoteX8来审查文章并提取数据。审查后,对这些研究进行了分析和分类.两种方法无统计学差异,激光和微针刺,在60%的研究文章中,萎缩性和肥厚性疤痕的治疗,并且两者都显示出显着的改善(完全反应改善了70%或更多)。在针对激光和微针刺治疗方法进行的研究中,有20%的研究得到了显着改善。这项研究的结果表明,在60%的研究中,针刺和烧蚀分数激光是可以忍受和安全的程序,在皮肤疤痕的治疗中没有显着差异。
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