关键词: dorsomedial prefrontal cortex fMRI loss aversion social cognitive intervention social decision

Mesh : Humans Brain / diagnostic imaging physiology Prefrontal Cortex / diagnostic imaging physiology Choice Behavior / physiology Brain Mapping Gambling Magnetic Resonance Imaging Decision Making / physiology

来  源:   DOI:10.1093/cercor/bhad025

Abstract:
Despite the ubiquitous interdependence between one\'s own decisions and others\' welfare, and the controversial evidence on the behavioral effect of choosing for others, the neural bases of making decisions for another versus oneself remain unexplored. We investigated whether loss aversion (LA; the tendency to avoid losses over approaching equivalent gains) is modulated by (i) choosing for oneself, other individuals, or both; (ii) knowing or not knowing the other recipients; or (iii) an interaction between these factors. We used fMRI to assess the brain activations associated with choosing whether to accept or reject mixed gambles, either for oneself, for another player, or both, in 2 groups of 28 participants who had or had not briefly interacted with the other players before scanning. Participants displayed higher LA for choices involving their payoff compared with those affecting only the payoff of other, known, players. This \"social\" modulation of decision-making was found to engage the dorsomedial prefrontal cortex and its inhibitory connectivity to the middle cingulate cortex. This pattern might underpin decision-making for known others via self-other distinction processes associated with dorsomedial prefrontal areas, with this in turn promoting the inhibition of socially oriented responses through the downregulation of the midcingulate node of the empathy network.
摘要:
尽管自己的决定和他人的福利之间普遍存在着相互依存的关系,以及关于为他人选择的行为效应的有争议的证据,为他人和自己做决定的神经基础仍未被探索。我们调查了损失厌恶(LA;避免损失超过接近等效收益的倾向)是否通过(i)为自己选择来调节,其他个人,或两者;(ii)知道或不知道其他接收者;或(iii)这些因素之间的相互作用。我们使用功能磁共振成像来评估与选择接受或拒绝混合赌博相关的大脑激活,要么是为了自己,对于另一个玩家来说,或者两者兼而有之,在2组28名参与者中,这些参与者在扫描前与其他参与者有或没有短暂互动。与仅影响其他收益的选择相比,参与者在涉及收益的选择中表现出更高的LA,已知,玩家。发现这种决策的“社会”调节与背内侧前额叶皮层及其与中扣带皮层的抑制性连接有关。这种模式可能通过与背内侧前额叶区域相关的自我区分过程来支持已知其他人的决策,反过来,通过对移情网络的中扣带节点的下调,促进了对社会导向反应的抑制。
公众号