PDF(Pubmed)
Abstract：
UNASSIGNED: Pulmonary hemorrhage (PH) is one kind of critical lung diseases in newborn infants, which is the most difficult one to be diagnosed by ultrasound. This study was to investigate the specific ultrasonic signs of PH in order to better diagnose neonatal PH by using lung ultrasound (LUS).
UNASSIGNED: A total 168 newborn infants were enrolled in this study, which included PH, pneumonia, meconium aspiration syndrome, and newborns without lung diseases, there were 42 cases in each group. In a quiet state, infants were placed in the supine, lateral or prone position for the examination. Each lung was divided into the anterior, lateral and posterior regions, then each region of both lungs was scanned with the probe perpendicular to the ribs or parallel to the Intercostal spaces.
UNASSIGNED: The major results showed that: (1) the common LUS manifestation of PH includes lung consolidation, air bronchograms, fluid bronchograms, pleural effusion, shred signs, pleural line abnormality and B-lines, while fibrin deposition sign is a rare sign of PH. (2) Co-existing of lung consolidation with fluid bronchograms and pleural effusion is the specific sign of PH with a sensitivity of 81.0%, specificity of 98.4% and the positive predictive value (PPV) was 94.4%. (3) Fibrin deposition sign is an uncommon specific LUS sign of PH with a sensitivity 28.6%, specificity of 100% and the PPV was 100%. (4) Nine patients (21.4%) were diagnosed with PH based on ultrasound findings before oronasal bleeding. (5) The survival rate of infants with PH was 100% in this study.
UNASSIGNED: LUS is helpful for the early diagnosis of neonatal PH and may therefore improve the prognosis. The lung consolidation with fluid bronchograms and pleural effusion as well as fibrin deposition sign are specific to diagnose PH by using LUS.
UNASSIGNED: A total 168 newborn infants were enrolled in this study, which included PH, pneumonia, meconium aspiration syndrome, and newborns without lung diseases, there were 42 cases in each group. In a quiet state, infants were placed in the supine, lateral or prone position for the examination. Each lung was divided into the anterior, lateral and posterior regions, then each region of both lungs was scanned with the probe perpendicular to the ribs or parallel to the Intercostal spaces.
UNASSIGNED: The major results showed that: (1) the common LUS manifestation of PH includes lung consolidation, air bronchograms, fluid bronchograms, pleural effusion, shred signs, pleural line abnormality and B-lines, while fibrin deposition sign is a rare sign of PH. (2) Co-existing of lung consolidation with fluid bronchograms and pleural effusion is the specific sign of PH with a sensitivity of 81.0%, specificity of 98.4% and the positive predictive value (PPV) was 94.4%. (3) Fibrin deposition sign is an uncommon specific LUS sign of PH with a sensitivity 28.6%, specificity of 100% and the PPV was 100%. (4) Nine patients (21.4%) were diagnosed with PH based on ultrasound findings before oronasal bleeding. (5) The survival rate of infants with PH was 100% in this study.
UNASSIGNED: LUS is helpful for the early diagnosis of neonatal PH and may therefore improve the prognosis. The lung consolidation with fluid bronchograms and pleural effusion as well as fibrin deposition sign are specific to diagnose PH by using LUS.
摘要：
未经证实：肺出血（PH）是新生儿的一种危重肺部疾病，这是最困难的超声诊断。本研究旨在探讨PH的具体超声征象，以便利用肺部超声（LUS）更好地诊断新生儿PH。
未经评估：本研究共纳入168名新生儿，其中包括PH，肺炎,胎粪吸入综合征,和没有肺部疾病的新生儿，每组42例。在安静的状态下，婴儿被放在仰卧，用于检查的侧卧位或俯卧位。每个肺被分成前部，外侧和后部区域，然后用探头垂直于肋骨或平行于肋间空间扫描两肺的每个区域。
未经证实：主要结果表明：（1）PH的常见LUS表现包括肺实变，空气支气管图,液体支气管图,胸腔积液,shredsigns,胸膜线异常和B线，而纤维蛋白沉积征是一种罕见的PH征象。（2）肺实变与支气管积液和胸腔积液并存是PH的特异性征象，敏感性为81.0%，特异性为98.4%,阳性预测值(PPV)为94.4%。(3)纤维蛋白沉积征是一种少见的PH特异性LUS征象,灵敏度为28.6%,特异性为100%，PPV为100%。（4）9例（21.4％）根据口鼻出血前的超声检查结果诊断为PH。(5)本研究中PH患儿的存活率为100%。
UNASSIGNED：LUS有助于新生儿PH的早期诊断，可改善预后。通过使用LUS来诊断PH，具有支气管积液和胸腔积液以及纤维蛋白沉积体征的肺实变是特定的。
未经评估：本研究共纳入168名新生儿，其中包括PH，肺炎,胎粪吸入综合征,和没有肺部疾病的新生儿，每组42例。在安静的状态下，婴儿被放在仰卧，用于检查的侧卧位或俯卧位。每个肺被分成前部，外侧和后部区域，然后用探头垂直于肋骨或平行于肋间空间扫描两肺的每个区域。
未经证实：主要结果表明：（1）PH的常见LUS表现包括肺实变，空气支气管图,液体支气管图,胸腔积液,shredsigns,胸膜线异常和B线，而纤维蛋白沉积征是一种罕见的PH征象。（2）肺实变与支气管积液和胸腔积液并存是PH的特异性征象，敏感性为81.0%，特异性为98.4%,阳性预测值(PPV)为94.4%。(3)纤维蛋白沉积征是一种少见的PH特异性LUS征象,灵敏度为28.6%,特异性为100%，PPV为100%。（4）9例（21.4％）根据口鼻出血前的超声检查结果诊断为PH。(5)本研究中PH患儿的存活率为100%。
UNASSIGNED：LUS有助于新生儿PH的早期诊断，可改善预后。通过使用LUS来诊断PH，具有支气管积液和胸腔积液以及纤维蛋白沉积体征的肺实变是特定的。
