关键词: COVID-19 Corneal transplantation eye donation lockdown

Mesh : Humans Middle Aged Corneal Diseases / epidemiology surgery COVID-19 / epidemiology Descemet Stripping Endothelial Keratoplasty / methods Eye Banks / methods Graft Survival Keratoplasty, Penetrating Pandemics Retrospective Studies Tissue and Organ Procurement / trends

来  源:   DOI:10.4103/ijo.IJO_1368_22   PDF(Pubmed)

Abstract:
To analyze the impact on eye donation and corneal transplantation during the COVID-19 pandemic in a tertiary eye hospital in south India.
A retrospective analysis of the donor and recipient records during the study period from January 2020 to May 2021 was conducted and tabulated in Microsoft Excel 2013. Demographic details of the donor, utility rate, cause of death, culture characteristics, storage methods, wet lab usage, and the surgical donor outcomes were evaluated. Additionally, the postoperative workup of the recipients, diagnosis, graft infection and rejection episodes, development of COVID-19 postoperatively, and outcome in terms of visual acuity at one, three, and six months were also noted.
A total of 466 eyes from 249 donors were received during the study period. The mean age of the donor population was 62.43 years (20.9). The corneal transplantation utility rate was 36.4% (n = 170). Fifty-one percent of the total transplant surgeries were for therapeutic purposes. This was followed by penetrating optical keratoplasty (34%), Descemet\'s stripping endothelial keratoplasty (9%), and patch grafts (3%). Seventeen (10%) graft rejection episodes were noted and nine (53%) had complete resolution after medical treatment.
Proper preventive measures are key to carrying out safe and efficient eye banking activities even during a deadly pandemic, as COVID-19 transmission via transplantation is rare.
摘要:
UNASSIGNED:分析印度南部一家三级眼科医院在COVID-19大流行期间对眼部捐赠和角膜移植的影响。
UNASSIGNED:在2020年1月至2021年5月的研究期间,对捐赠者和接受者的记录进行了回顾性分析,并在MicrosoftExcel2013中列出。捐赠者的人口统计细节,公用事业费率,死因,文化特色,存储方法,湿实验室的使用,并对手术供体结果进行评估.此外,接受者的术后检查,诊断,移植物感染和排斥反应,术后COVID-19的发展,以及以视力为单位的结果,三,还注意到六个月。
UNASSIGNED:在研究期间共接收了来自249个供体的466只眼。供者群体的平均年龄为62.43岁(20.9岁)。角膜移植使用率为36.4%(n=170)。整个移植手术中有51%用于治疗目的。其次是穿透性光学角膜移植术(34%),Descemet's剥脱内皮角膜移植术(9%),和贴片移植物(3%)。注意到17次(10%)移植排斥反应发作,9次(53%)在药物治疗后完全消退。
UNASISIGNED:适当的预防措施是即使在致命的大流行期间也能安全有效地开展眼库活动的关键,因为COVID-19通过移植传播很少。
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