PDF(Pubmed)
Abstract：
UNASSIGNED: Cold stress adversely affects the growth and development of plants and limits the geographical distribution of many plant species. Accumulation of spontaneous mutations shapes the adaptation of plant species to diverse climatic conditions.
UNASSIGNED: The genome-wide association study of the phenotypic variation gathered by a newly designed phenomic platform with the over six millions single nucleotide polymorphic (SNP) loci distributed across the genomes of 417 Arabidopsis natural variants collected from various geographical regions revealed 33 candidate cold responsive genes.
UNASSIGNED: Investigation of at least two independent insertion mutants for 29 genes identified 16 chilling tolerance genes governing diverse genetic mechanisms. Five of these genes encode novel leucine-rich repeat domain-containing proteins including three nucleotide-binding site-leucine-rich repeat (NBS-LRR) proteins. Among the 16 identified chilling tolerance genes, ADS2 and ACD6 are the only two chilling tolerance genes identified earlier.
UNASSIGNED: The 12.5% overlap between the genes identified in this genome-wide association study (GWAS) of natural variants with those discovered previously through forward and reverse genetic approaches suggests that chilling tolerance is a complex physiological process governed by a large number of genetic mechanisms.
UNASSIGNED: The genome-wide association study of the phenotypic variation gathered by a newly designed phenomic platform with the over six millions single nucleotide polymorphic (SNP) loci distributed across the genomes of 417 Arabidopsis natural variants collected from various geographical regions revealed 33 candidate cold responsive genes.
UNASSIGNED: Investigation of at least two independent insertion mutants for 29 genes identified 16 chilling tolerance genes governing diverse genetic mechanisms. Five of these genes encode novel leucine-rich repeat domain-containing proteins including three nucleotide-binding site-leucine-rich repeat (NBS-LRR) proteins. Among the 16 identified chilling tolerance genes, ADS2 and ACD6 are the only two chilling tolerance genes identified earlier.
UNASSIGNED: The 12.5% overlap between the genes identified in this genome-wide association study (GWAS) of natural variants with those discovered previously through forward and reverse genetic approaches suggests that chilling tolerance is a complex physiological process governed by a large number of genetic mechanisms.
摘要：
未经证实：冷胁迫对植物的生长和发育产生不利影响，并限制了许多植物物种的地理分布。自发突变的积累决定了植物物种对不同气候条件的适应。
UNASSIGNED：通过新设计的表型平台收集的表型变异的全基因组关联研究，该平台具有超过600万个单核苷酸多态性（SNP）基因座，分布在从各个地理区域收集的417个拟南芥自然变体的基因组中，揭示了33个候选冷响应基因。
UNASSIGNED：对29个基因的至少两个独立插入突变体的调查发现了16个控制不同遗传机制的耐寒性基因。这些基因中的五个编码新的富含亮氨酸的重复结构域的蛋白质,包括三个核苷酸结合位点-富含亮氨酸的重复(NBS-LRR)蛋白质。在确定的16个耐寒性基因中，ADS2和ACD6是较早鉴定的仅有的两个耐寒性基因。
UNASSIGNED：在这项全基因组关联研究（GWAS）中确定的天然变异基因与先前通过正向和反向遗传方法发现的基因之间有12.5％的重叠，这表明耐寒性是由大量遗传机制控制的复杂生理过程。
UNASSIGNED：通过新设计的表型平台收集的表型变异的全基因组关联研究，该平台具有超过600万个单核苷酸多态性（SNP）基因座，分布在从各个地理区域收集的417个拟南芥自然变体的基因组中，揭示了33个候选冷响应基因。
UNASSIGNED：对29个基因的至少两个独立插入突变体的调查发现了16个控制不同遗传机制的耐寒性基因。这些基因中的五个编码新的富含亮氨酸的重复结构域的蛋白质,包括三个核苷酸结合位点-富含亮氨酸的重复(NBS-LRR)蛋白质。在确定的16个耐寒性基因中，ADS2和ACD6是较早鉴定的仅有的两个耐寒性基因。
UNASSIGNED：在这项全基因组关联研究（GWAS）中确定的天然变异基因与先前通过正向和反向遗传方法发现的基因之间有12.5％的重叠，这表明耐寒性是由大量遗传机制控制的复杂生理过程。
