PDF(Pubmed)
Abstract：
Extramammary Paget\'s Disease (EMPD) is a rare cutaneous, slow growing, intraepithelial adenocarcinoma that can be either primary (intraepithelial arising within the epidermis) or secondary (intraepithelial spread of a visceral carcinoma). Here we present the case of a 63-year-old male with EMPD of the glans penis stemming from underlying urothelial carcinoma. Our treatment decision elected for management with chemotherapy and local treatment with radiation therapy. Subsequent, review of the literature demonstrated a rare disease with a variety of underlying malignancies causing this secondary pathology. Caregivers should be aware of the association of Paget\'s disease and urothelial cancer and should have a high index of suspicion that erythematous penile lesions may represent Paget\'s disease and that penile biopsies should be performed early in this setting.
摘要：
乳房外Paget病(EMPD)是一种罕见的皮肤疾病,生长缓慢,上皮内腺癌，可以是原发性（上皮内出现在表皮内）或继发性（内脏癌的上皮内扩散）。在这里，我们介绍了一名63岁的男性，其龟头EMPD源于潜在的尿路上皮癌。我们的治疗决定选择化疗和放疗局部治疗。随后,对文献的回顾表明，一种罕见的疾病与各种潜在的恶性肿瘤引起这种继发性病理。看护者应该意识到Paget病和尿路上皮癌的关联，并且应该高度怀疑红斑性阴茎病变可能代表Paget病，并且应该在这种情况下早期进行阴茎活检。
