Abstract:
We report the successful treatment of poxvirus lesions in two juvenile American flamingos (Phoenicopterus ruber) with experimental low-dose intralesional ribavirin injection. In the first flamingo, the size and location of a beak verrucosity interfered with feeding, and after multiple surgical interventions, an experimental therapy of low-dose intralesional ribavirin was implemented with close blood parameter monitoring to minimize any potential side effects due to systemic antiviral administration. The second flamingo had a poxvirus lesion on the tibiotarsus, which recurred after unsuccessful conservative medical treatment and surgical intervention and a course of intralesional ribavirin therapy was implemented. Regression of the lesions in both flamingos commenced within 3 days of ribavirin treatment resulting in complete resolution within 6 weeks of onset of ribavirin treatment.
摘要:
我们报告了通过实验性低剂量病灶内注射利巴韦林成功治疗了两只美国幼年火烈鸟(Phoenicopterusruber)的痘病毒病变。在第一个火烈鸟中,喙疣的大小和位置干扰了进食,在多次手术干预后,我们在密切血液参数监测的情况下实施了低剂量利巴韦林病灶内治疗,以最大限度地减少由于全身抗病毒给药引起的任何潜在副作用.第二个火烈鸟在胫骨上有痘病毒病变,在保守药物治疗和手术干预失败后复发,并实施了一个疗程的病灶内利巴韦林治疗。两个火烈鸟的病变在利巴韦林治疗的3天内开始消退,导致在利巴韦林治疗开始的6周内完全消退。