PDF(Pubmed)
Abstract：
Not all blockchains are created equal, and many cannot accommodate all of the primary characteristics of big data: Variety, Velocity, Volume and Veracity. Currently, public blockchains are slow and clunky, it can be expensive to keep up with the velocity of genomic data production. Further, the transparent and universally accessible nature of public blockchain doesn\'t necessarily accommodate all of the variety of sequence data, including very private information. Bespoke private permissioned blockchains, however, can be created to optimally accommodate all of the big data features of genomic data. Further, private permissioned chains can be implemented to both protect the privacy and security of the genetic information therein, while also providing access to researchers. An NFT marketplace associated with that private chain can provide the discretized sale of anonymous and encrypted data sets while also incentivizing individuals to share their data through payments mediated by smart contracts. Private blockchains can provide a transparent chain of custody for each use of the customers\' data, and validation that this data is not corrupted. However, even with all of these benefits there remain some concerns with the implementation of this new technology including the ethical, legal and social implications typically associated with DNA databases.
摘要：
并非所有的区块链都是平等的，许多人无法适应大数据的所有主要特征：多样性，速度,体积和准确性。目前,公共区块链既缓慢又笨重，跟上基因组数据产生的速度可能是昂贵的。Further,公共区块链的透明和普遍可访问的性质不一定能容纳所有种类的序列数据，包括非常私人的信息。定制私人许可的区块链，然而,可以创建以最佳地适应基因组数据的所有大数据特征。Further,可以实施私人许可链，以保护其中遗传信息的隐私和安全，同时也提供给研究人员。与该私有链相关的NFT市场可以提供匿名和加密数据集的离散化销售，同时还可以激励个人通过智能合约介导的支付共享数据。私有区块链可以为客户数据的每次使用提供透明的监管链，并验证此数据未损坏。然而,即使有所有这些好处，对这项新技术的实施仍然存在一些担忧，包括道德，通常与DNA数据库相关的法律和社会影响。
