Common variable immunodeficiency with granulomatous-lymphocytic interstitial lung disease treated with monoclonal antibodies against COVID-19: A case report.

用抗 COVID - 19 单克隆抗体治疗肉芽肿性淋巴细胞间质性肺病的常见可变免疫缺陷 ： 一例病例报告。

• 发表时间: Jan 2023
• 来源期刊: Clin Case Rep
• DOI: 10.1002/ccr3.6776
• PMID: 36703774
• 文章类型: Case Reports
• 作者列表: Lechner C,Zöggeler T,Bellmann R,Brunner J,Zlamy M,Schirmer M

关键词: COVID‐19; CVID; GLILD; molnupiravir; primary immunodeficiency; sotrovimab

Abstract

Common variable immunodeficiency (CVID) is the most prevalent primary immunodeficiency. We present a 22-year-old Caucasian woman with CVID and granulomatous lymphocytic interstitial lung disease who contracted COVID-19 and was successfully treated with sotrovimab and molnupiravir. This treatment may have contributed to the relatively mild disease course of COVID-19 in our patient.

摘要

常见可变免疫缺陷（CVID）是最常见的原发性免疫缺陷。我们介绍了一名22岁的高加索女性，患有CVID和肉芽肿性淋巴细胞性间质性肺病，她感染了COVID-19，并成功接受了索特罗韦和莫诺比拉韦治疗。这种治疗可能导致我们患者的COVID-19病程相对温和。