In this study, KTRs were divided into those with or without periodontitis and in relation to the severity of periodontitis. A comprehensive medical and periodontal examination was performed and evaluated. Multivariate logistic regression was performed to examine possible risk factors for SP among KTRs.
A total of 100 KTRs were included in the analysis, of which 87% had periodontitis. Significant predictors of periodontitis were older age (OR = 1.07, 95% CI [1.01, 1.13], p = 0.016) and lower skeletal muscle mass (OR = 0.88, 95% CI [0.78, 0.99], p = 0.035). When examining periodontitis severity, predictors of SP (n = 21, 24%) were increased levels of uric acid (OR = 1.01, 95% CI [1.00, 1.02], p = 0.022) and dental plaque (OR = 1.04, 95% CI [1.01, 1.07], p = 0.013). In the subset analysis that included only KTRs with measured advanced glycation end products (AGE) (n = 47), 34% (n = 16) had SP. The predictors of SP were AGE (OR = 3.89, 95% CI [1.28, 11.82], p = 0.017) and dental plaque (OR = 1.07, 95% CI [1.01, 1.13], p = 0.028).
KTRs with SP had significantly higher uric acid levels and AGE, which may contribute to the systemic health status of this patient population.
方法:在本研究中,KTRs分为有或没有牙周炎以及与牙周炎严重程度有关的那些。进行了全面的医学和牙周检查并进行了评估。采用多因素logistic回归分析KTRs中SP的可能危险因素。
结果:总共100KTRs被纳入分析,其中87%患有牙周炎。牙周炎的重要预测因素是年龄较大(OR(95%CI)=1.07(1.01-1.13),P=0.016)和较低的骨骼肌质量(OR(95%CI)=0.88(0.78-0.99),P=0.035)。检查牙周炎严重程度时,SP的预测因子(n=21,24%)是尿酸水平升高(OR(95%CI)=1.01(1.00-1.02),P=0.022)和牙菌斑(OR(95%CI)=1.04(1.01-1.07),P=0.013)。在子集分析中,仅包括具有测量的晚期糖基化终产物(AGE)的KTRs(n=47),34%(n=16)有SP。SP的预测因素是年龄(OR(95%CI)=3.89(1.28-11.82),P=0.017)和牙菌斑(OR(95%CI)=1.07(1.01-1.13),P=0.028)。
结论:KTRs伴SP有明显较高的尿酸水平和AGE,这可能有助于该患者人群的全身健康状况。本文受版权保护。保留所有权利。