UNASSIGNED: The PubMed, Web of Science, EMBASE and CNKI databases were searched for relevant studies up to November 7, 2022. The primary and secondary outcomes were overall survival (OS) and disease-free survival (DFS), respectively. The hazard ratios (HRs) and 95% confidence intervals (CIs) were combined.
UNASSIGNED: A total of 3,803 patients from 11 studies were enrolled and analyzed. The combined results demonstrated elevated preoperative mGPS was significantly related to poorer OS (HR = 2.11, 95% CI: 1.83-2.44, P < 0.001) and DFS (HR = 1.70, 95% CI: 1.42-2.03, P < 0.001). Subgroup analysis for the OS further identified the predictive role of elevated preoperative mGPS for worse OS in NSCLC.
UNASSIGNED: Preoperative mGPS was significantly associated with prognosis in NSCLC and patients with elevated preoperative mGPS experienced poorer long-term survival.
未经授权:PubMed,WebofScience,截至2022年11月7日,在EMBASE和CNKI数据库中搜索相关研究。主要和次要结局是总生存期(OS)和无病生存期(DFS),分别。将风险比(HR)和95%置信区间(CIs)组合。
UNASSIGNED:共纳入11项研究的3,803例患者并进行分析。合并结果显示,术前mGPS升高与OS较差(HR=2.11,95%CI:1.83-2.44,P<0.001)和DFS(HR=1.70,95%CI:1.42-2.03,P<0.001)显着相关。OS的亚组分析进一步确定了术前mGPS升高对NSCLC不良OS的预测作用。
UNASSIGNED:术前mGPS与NSCLC的预后显著相关,术前mGPS升高的患者的长期生存率较差。