关键词: Cystic echinococcosis Echinococcus granulosus Indirect hemagglutination test Turkey

来  源:   DOI:10.18502/ijpa.v17i4.11279   PDF(Pubmed)

Abstract:
UNASSIGNED: Parasites of the genus Echinococcus are common worldwide and are important cestodes that cause serious infections in humans and animals. This retrospective study evaluated the indirect hemagglutination (IHA) test results of serum samples obtained from patients with a pre-diagnosis of cystic echinococcosis (CE) within ten years. In addition, the role of the IHA test results of the patients in the follow-up of the treatment and determining possible recurrences was investigated.
UNASSIGNED: The IHA test results of 2426 serum samples of patients with a pre-diagnosed CE admitted to Trakya University Health Center for Medical Research and Practice in Edirne, Turkey, between January 2011 and December 2020 were evaluated retrospectively. The data of 53 patients with CE who had medical treatment and/or postoperative follow-up serological records were evaluated.
UNASSIGNED: Of 2426 IHA tests, 376 (15.5%) were seropositive, and 2050 (84.5%) were seronegative. It was determined that 376 serum samples detected as positive belonged to 207 patients with CE. Of 207 CE patients, 109 (52.7%) were female and 98 (47.3%) were male. The most common organ involvement was the liver in 186 (89.9%) cases. Of 53 patients, 16 were considered relapse cases. The median follow-up period for 16 recurrent cases was 31.8 (1-77) months. Our results showed a statistically significant correlation between long-term serological follow-up and recurrence detection (P=0.034).
UNASSIGNED: Long-term serological follow-up after treatment is considered useful in determining possible recurrent cases. CE is an important public health problem for endemic regions, including our country, and we think our study results will contribute to the status and follow-up of the disease.
摘要:
未经证实:棘球蚴属寄生虫在世界范围内很常见,是引起人类和动物严重感染的重要昆虫。这项回顾性研究评估了十年内囊性包虫病(CE)预诊断患者血清样本的间接血凝(IHA)测试结果。此外,研究了患者IHA检测结果在治疗随访和确定可能复发中的作用.
UNASSIGNED:在埃迪尔内的Trakya大学医学研究与实践健康中心收治的2426例预先诊断为CE的患者血清样本的IHA测试结果,土耳其,在2011年1月至2020年12月期间进行了回顾性评估。评估了53例接受药物治疗和/或术后随访血清学记录的CE患者的数据。
未经评估:在2426项IHA测试中,376(15.5%)为血清阳性,2050年(84.5%)为血清阴性。确定检测为阳性的376份血清样品属于207例CE患者。在207例CE患者中,109(52.7%)为女性,98(47.3%)为男性。186例(89.9%)中最常见的器官受累是肝脏。53名患者中,16例被认为是复发病例。16例复发病例的中位随访期为31.8(1-77)个月。我们的结果显示,长期血清学随访与复发检测之间存在统计学上的显着相关性(P=0.034)。
UNASSIGNED:治疗后的长期血清学随访被认为有助于确定可能的复发病例。CE是流行地区的重要公共卫生问题,包括我们的国家,我们认为我们的研究结果将有助于疾病的状态和随访。
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