Abstract：
Loneliness and dementia are common among very old (aged ≥ 80 years) people, but whether the prevalence of loneliness differs between very old people with and without dementia is unknown and few studies have investigated associated factors. The aims of the present study were to compare the prevalence of loneliness between people with and without dementia in a representative sample of very old people, and to investigate factors associated with loneliness in the two groups separately. This population-based study was conducted with data on 1176 people aged 85, 90, and ≥ 95 years (mean age 89.0 ± 4.47 years) from the Umeå 85 + /Gerontological Regional Database study conducted in northern Sweden, during year 2000-2017. Structured interviews and assessments were conducted during home visits. Loneliness was assessed using the question \"Do you ever feel lonely?.\" Multivariable logistic regression analysis was conducted to identify factors associated with loneliness in participants with and without dementia. The prevalence of loneliness did not differ between people with and without dementia (50.9% and 46.0%, respectively; p = 0.13). Seven and 24 of 35 variables were univariately associated with the experience of loneliness in participants with and without dementia, respectively. In the final models, living alone and having depressive symptoms were associated with the experience of loneliness in both study groups. In participants without dementia, living in a nursing home was associated with the experience of less loneliness. These findings contribute with important knowledge when developing strategies to reduce loneliness in this growing age group.
摘要：
孤独感和痴呆在高龄（年龄≥80岁）人群中很常见，但是，孤独感的患病率是否在患有和不患有痴呆症的老年人之间有所不同尚不清楚，并且很少有研究调查相关因素。本研究的目的是比较有代表性的老年人样本中有痴呆症和没有痴呆症的人之间的孤独感患病率，并分别调查两组孤独感的相关因素。这项基于人群的研究是使用来自瑞典北部的于默奥85/老年学区域数据库研究的1176名年龄85、90和≥95岁（平均年龄89.0±4.47岁）的数据进行的，在2000-2017年期间。在家访期间进行了结构化的访谈和评估。孤独是用“你曾经感到孤独吗？”这个问题来评估的。进行了多变量逻辑回归分析，以确定有和没有痴呆的参与者的孤独感相关因素。孤独感的患病率在有和没有痴呆症的人之间没有差异(50.9%和46.0%，分别为；p=0.13)。35个变量中的7个和24个与有和没有痴呆症的参与者的孤独体验单变量相关，分别。在最终的模型中，在两个研究组中,独居和有抑郁症状与孤独感相关.在没有痴呆症的参与者中，生活在疗养院与减少孤独的经历有关。这些发现在制定减少这个不断增长的年龄段的孤独感的策略时提供了重要的知识。
