Abstract：
Cutaneous metastases from thyroid carcinomas are extremely rare; however, the scalp is a common site for cutaneous metastases from follicular thyroid carcinomas (FTCs). We report the case of a 77-year-old male patient with a blood-rich scalp lesion. Histopathological tests of punch biopsy specimens revealed subcutaneous well-formed follicular structures that were similar to those found in the thyroid gland. Immunohistochemistry using thyroid transcription factor-1 (TTF-1) and paired-box gene family 8 (PAX8) revealed an FTC metastasis. We performed total thyroidectomy and resection of the scalp lesion at the same time and administered postoperative radioactive iodine treatment. The primary thyroid lesion was diagnosed as an FTC based on extracapsular extension and vessel invasion. The patient has not experienced disease recurrence since the treatment. When scalp metastasis of thyroid carcinoma is suspected, we recommend total extirpation, including the primary tumor and scalp metastasis, for an improved prognosis.
摘要：
甲状腺癌的皮肤转移极为罕见；然而，头皮是滤泡性甲状腺癌（FTC）皮肤转移的常见部位。我们报告了一名77岁的男性患者，患有富含血液的头皮病变。穿刺活检标本的组织病理学检查显示皮下形成良好的滤泡结构，与甲状腺中的滤泡结构相似。使用甲状腺转录因子-1（TTF-1）和配对盒基因家族8（PAX8）的免疫组织化学显示FTC转移。我们同时进行了甲状腺全切除术和头皮病变切除术，并进行了术后放射性碘治疗。根据囊外延伸和血管侵犯，原发性甲状腺病变被诊断为FTC。患者自治疗以来未经历疾病复发。当怀疑甲状腺癌的头皮转移时，我们建议彻底消灭,包括原发肿瘤和头皮转移,改善预后。
