Abstract：
To investigate the effects of orthokeratology (ortho-k) lenses with aspheric and spherical base curve designs on corneal refractive power (CRP) and peripheral refraction.
Children aged 8 to 12 years with myopia between -0.75 D to -4.00 D, astigmatism ≤1.00 D, and corneal astigmatism ≤1.50 D were randomly assigned to the base curve aspheric (BCA) and base curve spherical (BCS) ortho-k lens groups. CRP was assessed for the central 8 mm cornea along horizontal and vertical meridians, and peripheral refraction was measured at 10°, 20°, and 30° along the nasal and temporal retina. Primary measurements included relative corneal refractive power change (RCRPC) and relative peripheral refraction change (RPRC).
The 3-month results of the 33 and 29 subjects (right eye only) in the BCA and BCS groups, respectively, were obtained. Nonsignificant differences were found in the baseline data between the two groups (p > 0.05). At the 3-month follow-up visit, the mean RCRPC in the BCA group (2.08 ± 0.65 D) was significantly greater than that in the BCS group (1.32 ± 0.81 D) (F1,51 = 25.25, p < 0.001). The BCA group (-1.82 ± 0.65 D) exhibited a larger absolute RPRC than the BCS group (-0.98 ± 0.54 D) (F1,57 = 33.73, p < 0.001).
It was found that the BCA ortho-k lens resulted in a more aspheric treatment zone and a more myopic relative peripheral refraction (RPR) along the horizontal meridian. The more myopic RPR was contributed by a more hyperopic central refraction and a more myopic peripheral refraction in the BCA group.
Children aged 8 to 12 years with myopia between -0.75 D to -4.00 D, astigmatism ≤1.00 D, and corneal astigmatism ≤1.50 D were randomly assigned to the base curve aspheric (BCA) and base curve spherical (BCS) ortho-k lens groups. CRP was assessed for the central 8 mm cornea along horizontal and vertical meridians, and peripheral refraction was measured at 10°, 20°, and 30° along the nasal and temporal retina. Primary measurements included relative corneal refractive power change (RCRPC) and relative peripheral refraction change (RPRC).
The 3-month results of the 33 and 29 subjects (right eye only) in the BCA and BCS groups, respectively, were obtained. Nonsignificant differences were found in the baseline data between the two groups (p > 0.05). At the 3-month follow-up visit, the mean RCRPC in the BCA group (2.08 ± 0.65 D) was significantly greater than that in the BCS group (1.32 ± 0.81 D) (F1,51 = 25.25, p < 0.001). The BCA group (-1.82 ± 0.65 D) exhibited a larger absolute RPRC than the BCS group (-0.98 ± 0.54 D) (F1,57 = 33.73, p < 0.001).
It was found that the BCA ortho-k lens resulted in a more aspheric treatment zone and a more myopic relative peripheral refraction (RPR) along the horizontal meridian. The more myopic RPR was contributed by a more hyperopic central refraction and a more myopic peripheral refraction in the BCA group.
摘要：
背景：研究具有非球面和球面基本曲线设计的角膜塑形镜（ortho-k）对角膜屈光力（CRP）和周边屈光的影响。
方法：8至12岁的儿童近视在-0.75D至-4.00D之间，散光≤1.00D，角膜散光≤1.50D被随机分配到基础曲线非球面（BCA）和基础曲线球面（BCS）正交透镜组。沿水平和垂直经络评估中央8毫米角膜的CRP，在10°测量周边屈光度，20°,沿着鼻部和颞部视网膜30°。主要测量包括相对角膜屈光力变化(RCRPC)和相对周边屈光力变化(RPRC)。
结果：BCA和BCS组中33和29名受试者（仅右眼）的3个月结果，分别,已获得。两组患者基线资料差异无统计学意义(p>0.05)。在为期3个月的随访中，BCA组的平均RCRPC（2.08±0.65D）明显大于BCS组（1.32±0.81D）（F1,51=25.25，p<0.001）。BCA组(-1.82±0.65D)的绝对RPRC高于BCS组(-0.98±0.54D)(F1,57=33.73,p<0.001)。
结论：发现BCA正k晶状体导致沿水平子午线的更非球面的治疗区和更近视的相对外周屈光度（RPR）。在BCA组中，远视中心屈光和近视周围屈光对近视RPR的贡献更大。
方法：8至12岁的儿童近视在-0.75D至-4.00D之间，散光≤1.00D，角膜散光≤1.50D被随机分配到基础曲线非球面（BCA）和基础曲线球面（BCS）正交透镜组。沿水平和垂直经络评估中央8毫米角膜的CRP，在10°测量周边屈光度，20°,沿着鼻部和颞部视网膜30°。主要测量包括相对角膜屈光力变化(RCRPC)和相对周边屈光力变化(RPRC)。
结果：BCA和BCS组中33和29名受试者（仅右眼）的3个月结果，分别,已获得。两组患者基线资料差异无统计学意义(p>0.05)。在为期3个月的随访中，BCA组的平均RCRPC（2.08±0.65D）明显大于BCS组（1.32±0.81D）（F1,51=25.25，p<0.001）。BCA组(-1.82±0.65D)的绝对RPRC高于BCS组(-0.98±0.54D)(F1,57=33.73,p<0.001)。
结论：发现BCA正k晶状体导致沿水平子午线的更非球面的治疗区和更近视的相对外周屈光度（RPR）。在BCA组中，远视中心屈光和近视周围屈光对近视RPR的贡献更大。
