Abstract：
Background and Objectives: Asthma constitutes a constant, prolonged, inflammation-related pulmonary disorder in childhood with serious public health concerns. Several maternal risk factors can enhance the prevalence of its development in this stage of life; however, the currently available data remain contradictory and/or inconsistent. We aim to evaluate the potential impacts of mothers\' sociodemographic, anthropometric and prenatal and perinatal factors on the prevalence of developing asthma in pre-school children. Materials and Methods: This is a retrospective cross-sectional survey, which includes 5133 women and their matched pre-school children. Childhood asthma was diagnosed using validated questionnaires. Statistical analysis was accomplished to evaluate whether maternal sociodemographic, anthropometric and prenatal and perinatal factors can increase the probability of childhood asthma in pre-school age. Results: A prevalence of 4.5% of childhood asthma was recorded in pre-school age. Maternal age and pre-pregnancy overweight and obesity, caesarean section, gestational diabetes and hypertension and not breastfeeding were associated with childhood asthma after adjustment for multiple confounding factors. Conclusion: Our research showed that several maternal factors increase the prevalence of childhood asthma in pre-school age. Suitable and effective health policies and strategies should be taken into account to confront the predominant maternal factors that increase its prevalence in pre-school age.
摘要：
背景和目的：哮喘是一个常数，延长,儿童炎症相关的肺部疾病与严重的公共卫生问题。几个母亲的风险因素可以提高其发展的患病率在这一阶段的生活;然而，当前可用的数据仍然矛盾和/或不一致。我们的目标是评估母亲社会人口统计学的潜在影响，人体测量和产前和围产期因素对学龄前儿童哮喘患病率的影响。材料和方法：这是一项回顾性的横断面调查，其中包括5133名妇女及其匹配的学龄前儿童。使用经过验证的问卷诊断儿童哮喘。完成了统计分析，以评估产妇的社会人口统计学，人体测量和产前和围产期因素可以增加学龄前儿童哮喘的概率。结果：学龄前儿童哮喘的患病率为4.5％。产妇年龄和孕前超重和肥胖，剖腹产,在校正了多种混杂因素后,妊娠期糖尿病和高血压以及非母乳喂养与儿童哮喘相关.结论：我们的研究表明，几个母亲因素增加了学龄前儿童哮喘的患病率。应考虑到适当和有效的卫生政策和战略，以应对在学龄前增加其患病率的主要孕产妇因素。
