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Abstract：
This review discusses chiral-at-metal complexes and introduces enantiomorphs from assembly structure. Owing to the diverse coordination number and activity of metal ions as chiral centers, abundant structures for chiral selectivity, catalysis, and polarized light-response are the notable advantages of the chiral-at-metal complexes. The rational design and preparation of linear multi-dentate ligands is a good choice to improve the stability of chiral complexes, such as multi-bonding structure for high stability as a self-limiting system. The bio-significance and potential application of chiral-at-metal complexes are discussed, such as the synergistic effect of catalysis and chiral selectivity of the metal center in enzymes. Enzyme could be remolded to replace the original central metal ions with highly active rare earth or precious metal ions to form artificial metalloenzyme or to remove the \"redundant\" part around the metal center to improve the accessibility of substrate. The polarized light-response mechanism of chiral opsin is introduced in relation to its role in animal migration. Metal-organic frameworks (MOFs) are crystalline and porous materials built from metal nodes or clusters and organic linkers and provide the possibility to prepare artificial enantiomorphs. The preparations, applications, and characterization methods of MOF enatiomorphs are therefore introduced. We hope this review inspires researchers at all levels of their career to consider the title topic in their own research in terms of its application and potential value.
摘要：
本文讨论了手性金属配合物，并从组装结构介绍了对映体。由于金属离子作为手性中心的不同配位数和活性，丰富的手性选择性结构，催化作用,和偏振光响应是手性金属配合物的显着优势。线性多齿配体的合理设计和制备是提高手性配合物稳定性的良好选择,如多键合结构作为自限制系统的高稳定性。讨论了手性金属配合物的生物意义和潜在应用，如酶中金属中心的催化和手性选择性的协同作用。酶可以被重塑，用高活性的稀土或贵金属离子代替原来的中心金属离子，形成人工金属酶或去除金属中心周围的“多余”部分，以提高底物的可及性。介绍了手性视蛋白的偏振光响应机制及其在动物迁移中的作用。金属有机骨架（MOF）是由金属节点或簇和有机连接基构建的晶体和多孔材料，为制备人工对映体提供了可能性。准备工作,应用程序,并介绍了MOF局部形态的表征方法。我们希望这篇评论能激发职业生涯各个层面的研究人员在自己的研究中考虑标题主题的应用和潜在价值。
