PDF(Pubmed)
Abstract：
UNASSIGNED: Synthesized Mammogram (SM) from Digital Breast Tomosynthesis (DBT) images is introduced to replace the routine Full Field Digital Mammography (FFDM) to reduce radiation dose.
UNASSIGNED: to compare the conspicuity of cancer related findings between SM and FFDM and combination of these methods with DBT.
UNASSIGNED: The study was conducted in a tertiary breast imaging center, where 200 women referred for screening were enrolled in the study sequentially. Patients underwent FFDM and DBT simultaneously and a two-year follow-up was done. Data was evaluated for Breast Imaging Reporting and Data System (BI-RADS) score, breast density, mass lesions, calcification, and focal asymmetry by two expert breast radiologists. Comparison between different methods was made by Cohen Kappa test.
UNASSIGNED: 22 patients with likely malignant findings went under biopsy. Taking histopathologic findings and two-year follow up as reference, the overall sensitivity and specificity for FFDM+DBT (86.1 and 88.9 respectively) and SM+DBT (86.1 and 88.2) didn\'t show a meaningful difference. Comparing SM and FFDM, calcification in 20 subjects were overlooked on SM, but later detected when combined with DBT. Considering breast composition and BI-RADS categorization, an excellent agreement existed between the readers.
UNASSIGNED: Screening with SM+DBT shows comparable results with FFDM+DBT considering BI-RADS categorization of the patients. Although SM showed slightly inferior sensitivity compared to FFDM, after combining DBT with SM no malignant appearing calcification or mass lesion was missed.
UNASSIGNED: to compare the conspicuity of cancer related findings between SM and FFDM and combination of these methods with DBT.
UNASSIGNED: The study was conducted in a tertiary breast imaging center, where 200 women referred for screening were enrolled in the study sequentially. Patients underwent FFDM and DBT simultaneously and a two-year follow-up was done. Data was evaluated for Breast Imaging Reporting and Data System (BI-RADS) score, breast density, mass lesions, calcification, and focal asymmetry by two expert breast radiologists. Comparison between different methods was made by Cohen Kappa test.
UNASSIGNED: 22 patients with likely malignant findings went under biopsy. Taking histopathologic findings and two-year follow up as reference, the overall sensitivity and specificity for FFDM+DBT (86.1 and 88.9 respectively) and SM+DBT (86.1 and 88.2) didn\'t show a meaningful difference. Comparing SM and FFDM, calcification in 20 subjects were overlooked on SM, but later detected when combined with DBT. Considering breast composition and BI-RADS categorization, an excellent agreement existed between the readers.
UNASSIGNED: Screening with SM+DBT shows comparable results with FFDM+DBT considering BI-RADS categorization of the patients. Although SM showed slightly inferior sensitivity compared to FFDM, after combining DBT with SM no malignant appearing calcification or mass lesion was missed.
摘要：
UNASSIGNED：采用数字乳腺断层合成（DBT）图像合成的乳房X线照片（SM）来代替常规的全场数字乳房X线摄影（FFDM），以减少辐射剂量。
UNASSIGNED：比较SM和FFDM之间癌症相关发现的显着性以及这些方法与DBT的组合。
UNASSIGNED：该研究是在三级乳腺成像中心进行的，其中200名转诊接受筛查的女性被依次纳入研究.患者同时接受FFDM和DBT，并进行为期两年的随访。评估乳腺影像报告和数据系统（BI-RADS）评分的数据，乳腺密度,肿块病变,钙化,和两位乳腺放射科专家的局灶性不对称。通过CohenKappa检验对不同方法进行比较。
未经证实：22例可能有恶性表现的患者进行了活检。以组织病理学发现和两年随访为参考，FFDM+DBT(分别为86.1和88.9)和SM+DBT(86.1和88.2)的总体敏感性和特异性没有显示有意义的差异.比较SM和FFDM，在SM上忽略了20名受试者的钙化，但后来与DBT结合时检测到。考虑到乳房成分和BI-RADS分类，读者之间有一个极好的协议。
UNASSIGNED：考虑到患者的BI-RADS分类，SM+DBT筛查与FFDM+DBT的结果相当。尽管与FFDM相比，SM的灵敏度略低，DBT与SM联合后，未发现恶性钙化或肿块。
UNASSIGNED：比较SM和FFDM之间癌症相关发现的显着性以及这些方法与DBT的组合。
UNASSIGNED：该研究是在三级乳腺成像中心进行的，其中200名转诊接受筛查的女性被依次纳入研究.患者同时接受FFDM和DBT，并进行为期两年的随访。评估乳腺影像报告和数据系统（BI-RADS）评分的数据，乳腺密度,肿块病变,钙化,和两位乳腺放射科专家的局灶性不对称。通过CohenKappa检验对不同方法进行比较。
未经证实：22例可能有恶性表现的患者进行了活检。以组织病理学发现和两年随访为参考，FFDM+DBT(分别为86.1和88.9)和SM+DBT(86.1和88.2)的总体敏感性和特异性没有显示有意义的差异.比较SM和FFDM，在SM上忽略了20名受试者的钙化，但后来与DBT结合时检测到。考虑到乳房成分和BI-RADS分类，读者之间有一个极好的协议。
UNASSIGNED：考虑到患者的BI-RADS分类，SM+DBT筛查与FFDM+DBT的结果相当。尽管与FFDM相比，SM的灵敏度略低，DBT与SM联合后，未发现恶性钙化或肿块。
