肝移植中排斥反应的生物标志物和分子诊断工具的现状 : 隧道尽头的光 ?
关键词: 3BMBs, third bifurcation mucosal endo-bronchial biopsies AMR, antibody mediated rejection APC, antigen presenting cells AR, Acute rejection ATCMR, acute T-cell mediated rejection ATG, Anti-thymoglobulin AUC, area under curve AUROC, area under receiver operating characteristic curve B-HOT, Banff Human Organ Transplant CNI, Calcineurin inhibitors DSA, Donor specific antibodies FDA, Food and drug administration FFPE, formalin fixed paraffin embedded preparation GLUT-4, glucose transport-4 HLA, human leukocyte antigens HNMR, high nuclear magnetic resonance ILTS, International liver transplantation society LT, Liver transplantation Liver transplantation MDWG, molecular diagnostic work group MFI, mean fluorescence intensity MHC, major histo–compatibility complex MMDX MMDX, Molecular microscopic diagnostic system MMF, Mycophenolate Mofetil MToR, Mechanistic target of Rapamycin NPV, Negative predictive value PPV, Positive predictive value RATs, rejection associated transcripts TBB, trans-bronchial biopsies UNOS, United network for organ sharing and procurement biomarker dd cfDNA, donor-derived cell-free DNA donor-derived cell-free DNA immune-suppression mRNA, messenger RNA miRNA, micro-RNA micro-RNA molecular diagnosis nano-string rejection
来 源:
DOI:10.1016/j.jceh.2022.06.010
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