Abstract：
Labial adhesions in postmenopausal women are caused by various inflammatory processes in the context of estrogen deficiency. Lichen sclerosus (LS) is a chronic, progressive condition characterized by idiopathic epithelial thinning of the anogenital region with symptoms of significant pruritus, discomfort, and dyspareunia. Early diagnosis and treatment of LS can prevent disease progression, leading to labial adhesions and malignancy. We present an 84-year-old woman with long-standing vulvar Hailey-Hailey disease who developed labial adhesions. Clinical examination with vulvar biopsy revealed histopathological findings consistent with LS. Surgical separation of the labia by blunt dissection was then performed, and clobetasol ointment and vaginal dilatators were postoperatively prescribed. This resulted in a significant improvement in her symptoms. This is the first reported case of LS in a patient with Hailey-Hailey disease.
摘要：
绝经后妇女的阴唇粘连是由雌激素缺乏的各种炎症过程引起的。硬化性苔藓(LS)是一种慢性、进行性疾病的特征是肛门生殖器区域的特发性上皮变薄，伴有明显瘙痒的症状，不适,和性交困难.早期诊断和治疗LS可以预防疾病进展，导致唇粘连和恶性肿瘤。我们介绍了一名84岁的女性，患有长期的外阴Hailey-Hailey病，并出现了唇粘连。外阴活检的临床检查显示组织病理学发现与LS一致。然后通过钝性解剖进行阴唇的手术分离，术后使用氯倍他索软膏和阴道扩张剂。这导致了她的症状的显著改善。这是Hailey-Hailey病患者中首例报告的LS病例。
