Abstract：
BACKGROUND: Depiction of bypass blood flow in patients who received extracranial-intracranial (EC-IC) bypass surgery is important for patient care.
OBJECTIVE: To develop a vessel-encoded arterial spin labeling (VE-ASL) method using surgical staples as a magnetic resonance (MR)-conditional product in patients who received EC-IC bypass surgery.
METHODS: Pseudo-continuous labeling was used for VE-ASL acquisition with a 3-T MR unit. First, an experimental study was conducted to determine the appropriate number of surgical staples to obtain a spatially sufficient saturation effect. Thereafter, four healthy normal volunteers underwent a VE-ASL study to confirm the sufficiency of the saturation effect to the right or left common carotid artery. Finally, VE-ASL scanning was performed in seven patients after EC-IC bypass surgery to confirm the ability of VE-ASL to visualize the territorial bypass perfusion. All qualitative evaluation was performed by two neuroradiologists using a 3-point grading system (2 = good, 1 = moderate, 0 = poor).
RESULTS: A quantity of 200 staples was found to be appropriate for VE-ASL scanning. In healthy volunteers, one neuroradiologist rated the images of all four cases as good, while the other rated three cases as good and one case as moderate. For the seven patients after EC-IC bypass surgery, one neuroradiologist rated all seven cases as good, and the other rated six cases as good and one case as moderate.
CONCLUSIONS: VE-ASL using surgical staples might be useful for the evaluation of territorial bypass perfusion in patients after EC-IC bypass surgery.
OBJECTIVE: To develop a vessel-encoded arterial spin labeling (VE-ASL) method using surgical staples as a magnetic resonance (MR)-conditional product in patients who received EC-IC bypass surgery.
METHODS: Pseudo-continuous labeling was used for VE-ASL acquisition with a 3-T MR unit. First, an experimental study was conducted to determine the appropriate number of surgical staples to obtain a spatially sufficient saturation effect. Thereafter, four healthy normal volunteers underwent a VE-ASL study to confirm the sufficiency of the saturation effect to the right or left common carotid artery. Finally, VE-ASL scanning was performed in seven patients after EC-IC bypass surgery to confirm the ability of VE-ASL to visualize the territorial bypass perfusion. All qualitative evaluation was performed by two neuroradiologists using a 3-point grading system (2 = good, 1 = moderate, 0 = poor).
RESULTS: A quantity of 200 staples was found to be appropriate for VE-ASL scanning. In healthy volunteers, one neuroradiologist rated the images of all four cases as good, while the other rated three cases as good and one case as moderate. For the seven patients after EC-IC bypass surgery, one neuroradiologist rated all seven cases as good, and the other rated six cases as good and one case as moderate.
CONCLUSIONS: VE-ASL using surgical staples might be useful for the evaluation of territorial bypass perfusion in patients after EC-IC bypass surgery.
摘要：
背景：在接受颅内外（EC-IC）搭桥手术的患者中，搭桥血流的描述对于患者护理很重要。
目的：开发一种血管编码动脉自旋标记（VE-ASL）方法，该方法使用外科钉作为磁共振（MR）条件产物，用于接受EC-IC搭桥手术的患者。
方法：伪连续标记用于3-TMR单元的VE-ASL采集。首先,进行了一项实验研究，以确定合适的手术钉数量，以获得空间上足够的饱和效果。此后,4名健康正常志愿者接受了VE-ASL研究,以确认右侧或左侧颈总动脉的饱和效应是否足够.最后,在EC-IC旁路手术后，对7例患者进行了VE-ASL扫描，以确认VE-ASL可视化区域旁路灌注的能力。所有定性评估均由两名神经放射科医生使用3分评分系统进行（2=良好，1=中度，0=差)。
结果：发现200个订书钉适合VE-ASL扫描。在健康的志愿者中，一位神经放射科医生对所有四个病例的图像进行了评价，而另一个则将三个案例评为良好，一个案例评为中等。对于接受EC-IC搭桥手术的7名患者，一位神经放射科医生对所有7例病例的评价都很好，另一个评为6例良好，一个评为中等。
结论：使用手术钉的VE-ASL可能有助于评估EC-IC旁路手术后患者的局部旁路灌注。
目的：开发一种血管编码动脉自旋标记（VE-ASL）方法，该方法使用外科钉作为磁共振（MR）条件产物，用于接受EC-IC搭桥手术的患者。
方法：伪连续标记用于3-TMR单元的VE-ASL采集。首先,进行了一项实验研究，以确定合适的手术钉数量，以获得空间上足够的饱和效果。此后,4名健康正常志愿者接受了VE-ASL研究,以确认右侧或左侧颈总动脉的饱和效应是否足够.最后,在EC-IC旁路手术后，对7例患者进行了VE-ASL扫描，以确认VE-ASL可视化区域旁路灌注的能力。所有定性评估均由两名神经放射科医生使用3分评分系统进行（2=良好，1=中度，0=差)。
结果：发现200个订书钉适合VE-ASL扫描。在健康的志愿者中，一位神经放射科医生对所有四个病例的图像进行了评价，而另一个则将三个案例评为良好，一个案例评为中等。对于接受EC-IC搭桥手术的7名患者，一位神经放射科医生对所有7例病例的评价都很好，另一个评为6例良好，一个评为中等。
结论：使用手术钉的VE-ASL可能有助于评估EC-IC旁路手术后患者的局部旁路灌注。
