Abstract:
White matter changes are seen in a spectrum of disorders in children and adolescents. Understanding their distribution and appearance helps to reach diagnoses in daily radiologic practice. This pictorial essay will outline the magnetic resonance imaging (MRI) appearances of diseases with white matter changes including demyelinating diseases, dysmyelinating disorders/leukodystrophies, infections, autoimmune diseases, vascular causes, mitochondrial disorders and neurocutaneous syndromes, along with a brief overview of clinical aspects of the diseases such as typical age of presentation, etiology, symptoms and signs and treatment options. This article highlights important features in common white matter diseases in children and adolescents.
摘要:
在儿童和青少年的一系列疾病中可以看到白质变化。了解它们的分布和外观有助于在日常放射学实践中进行诊断。这篇图片文章将概述包括脱髓鞘疾病在内的白质变化疾病的磁共振成像(MRI)表现,髓鞘障碍/脑白质营养不良,感染,自身免疫性疾病,血管原因,线粒体疾病和神经皮肤综合征,随着疾病的临床方面的简要概述,如典型的表现年龄,病因学,症状和体征和治疗选择。本文重点介绍了儿童和青少年常见白质疾病的重要特征。