Abstract:
This work presents the exposure of hands of the personnel of a nuclear medicine department who prepare and administer 68Ga-DOTA-TATE. Dosimetry measurements were performed during three 1-week sessions, for nine production procedures. A total of 360 measurements were made by using high-sensitivity MCP-N thermoluminescent detectors. Annealed detectors were and vacuum-packed in foil and then placed on each fingertip of both hands of five radiochemists and four nurses (one detector for one fingertip). The greatest exposure to ionizing radiation was found on the non-dominant left hand of radiochemists and nurses. A maximum Hp(0.07)/A value of 49.36 ± 4.95 mSv/GBq was registered for radiochemists during the 68 Ga-DOTA-DATE activity dispensing procedure. For nurses performing the radiopharmaceutical injection procedure, a corresponding maximum value of 1.28 ± 0.13 mSv/GBq was measured, while the mean value for all the nurses was 0.38 mSv/GBq. The dispensing procedure accounted for approximately 60% of the total exposure of radiochemists\' fingertips. Based on the results obtained it is recommended that a ring dosimeter should be routinely placed on the middle finger of the non-dominant hand of radiochemists and nurses. Furthermore, it is proposed to systematically train workers in handling open sources of ionizing radiation, with the aim of reducing the required handling time.
摘要:
这项工作介绍了准备和管理68Ga-DOTA-TATE的核医学部门人员的手。在三个为期1周的会议期间进行剂量学测量,九种生产程序。通过使用高灵敏度MCP-N热释光检测器进行了总共360次测量。将退火的检测器真空包装在箔中,然后将其放在五名放射化学家和四名护士的双手的每个指尖上(一个检测器用于一个指尖)。在放射化学家和护士的非优势左手上发现了最大的电离辐射暴露。在68Ga-DOTA-DATE活性分配过程中,放射化学家的最大Hp(0.07)/A值为49.36±4.95mSv/GBq。对于执行放射性药物注射程序的护士,测得的相应最大值为1.28±0.13mSv/GBq,而所有护士的平均值为0.38mSv/GBq。分配程序约占放射化学家指尖总暴露量的60%。根据获得的结果,建议将环形剂量计常规放置在放射化学家和护士的非优势手的中指上。此外,建议系统地培训工人处理公开的电离辐射源,目的是减少所需的处理时间。