PDF(Pubmed)
Abstract：
UNASSIGNED: Despite advances being made in techniques and devices, certain chronic total occlusion (CTO) lesions remain uncrossable or undilatable. Rotational atherectomy (RA) is usually necessary for such lesions to achieve successful revascularization.
UNASSIGNED: Information regarding consecutive patients who underwent coronary RA was retrieved from the catheterization laboratory database. Patients who underwent RA for CTO lesion refractory using other conventional devices were recruited, with propensity score-matched cases serving as controls.
UNASSIGNED: A total of 411 patients underwent coronary RA in the study period. Most patients had high-risk features (65.7% had acute coronary syndrome (ACS), 14.1% ischemic cardiomyopathy, and 5.1% cardiogenic shock), while only 20.2% of the patients had stable angina. Among them, 44 patients underwent RA for CTO lesions (CTO group), whereas the propensity score matched controls consist of 37 patients (non-CTO group). The baseline characteristics, high-risk features, coronary artery disease (CAD) vessel numbers, left ventricular function and biochemistry profiles of both groups were the same except for more patients with diabetes (67.6% vs. 45.5%, p = 0.046) in the non-CTO group and more 1.25 mm burr uses in the CTO group. There were no significant differences in acute procedural outcomes or incidence of acute contrast-induced nephropathy (CIN), and no patient demanded emergent CABG or died during the procedure. There was no significant difference in major adverse cardiovascular events (MACE), CV MACE or individual components between the two groups in the hospital, at 30, 90, and 180 days or at 1 year.
UNASSIGNED: In comparison with the propensity risk factor scores-matched controls, there was no difference in procedural complications, acute CIN or clinical outcomes during various stages of RA for CTO lesions. RA for CTO patients was highly efficient and showed safety and outcome profiles similar to those for non-CTO lesions.
UNASSIGNED: Information regarding consecutive patients who underwent coronary RA was retrieved from the catheterization laboratory database. Patients who underwent RA for CTO lesion refractory using other conventional devices were recruited, with propensity score-matched cases serving as controls.
UNASSIGNED: A total of 411 patients underwent coronary RA in the study period. Most patients had high-risk features (65.7% had acute coronary syndrome (ACS), 14.1% ischemic cardiomyopathy, and 5.1% cardiogenic shock), while only 20.2% of the patients had stable angina. Among them, 44 patients underwent RA for CTO lesions (CTO group), whereas the propensity score matched controls consist of 37 patients (non-CTO group). The baseline characteristics, high-risk features, coronary artery disease (CAD) vessel numbers, left ventricular function and biochemistry profiles of both groups were the same except for more patients with diabetes (67.6% vs. 45.5%, p = 0.046) in the non-CTO group and more 1.25 mm burr uses in the CTO group. There were no significant differences in acute procedural outcomes or incidence of acute contrast-induced nephropathy (CIN), and no patient demanded emergent CABG or died during the procedure. There was no significant difference in major adverse cardiovascular events (MACE), CV MACE or individual components between the two groups in the hospital, at 30, 90, and 180 days or at 1 year.
UNASSIGNED: In comparison with the propensity risk factor scores-matched controls, there was no difference in procedural complications, acute CIN or clinical outcomes during various stages of RA for CTO lesions. RA for CTO patients was highly efficient and showed safety and outcome profiles similar to those for non-CTO lesions.
摘要：
未经评估：尽管技术和设备取得了进步，某些慢性完全闭塞（CTO）病变仍不可交叉或不可扩张。旋转斑块切除术（RA）通常是此类病变成功实现血运重建的必要条件。
UASSIGNED：从导管插入实验室数据库检索关于连续接受冠状动脉RA患者的信息。招募使用其他常规装置治疗CTO难治病变的RA患者，以倾向得分匹配的病例作为对照。
未经证实：在研究期间共有411例患者接受了冠状动脉性RA。大多数患者具有高风险特征（65.7％患有急性冠状动脉综合征（ACS），14.1%缺血性心肌病，和5.1%心源性休克)，而只有20.2%的患者有稳定型心绞痛。其中,44例患者因CTO病变接受RA（CTO组），而倾向评分匹配的对照由37例患者(非CTO组)组成.基线特征，高风险特征，冠状动脉疾病（CAD）血管编号，除了更多的糖尿病患者外，两组的左心室功能和生化特征均相同（67.6％vs.45.5%,p=0.046）在非CTO组中，而在CTO组中使用更多1.25mm毛刺。急性手术结局或急性对比剂肾病（CIN）发生率无显著差异，并且没有患者要求紧急CABG或在手术过程中死亡。主要不良心血管事件（MACE）无显著差异，医院两组之间的CVMACE或单个组件，在30、90和180天或1年。
未经评估：与倾向风险因素得分匹配的对照相比，手术并发症没有差异，acuteCIN或RA不同阶段CTO病变的临床结果。CTO患者的RA非常有效，并且显示出与非CTO病变相似的安全性和结局特征。
UASSIGNED：从导管插入实验室数据库检索关于连续接受冠状动脉RA患者的信息。招募使用其他常规装置治疗CTO难治病变的RA患者，以倾向得分匹配的病例作为对照。
未经证实：在研究期间共有411例患者接受了冠状动脉性RA。大多数患者具有高风险特征（65.7％患有急性冠状动脉综合征（ACS），14.1%缺血性心肌病，和5.1%心源性休克)，而只有20.2%的患者有稳定型心绞痛。其中,44例患者因CTO病变接受RA（CTO组），而倾向评分匹配的对照由37例患者(非CTO组)组成.基线特征，高风险特征，冠状动脉疾病（CAD）血管编号，除了更多的糖尿病患者外，两组的左心室功能和生化特征均相同（67.6％vs.45.5%,p=0.046）在非CTO组中，而在CTO组中使用更多1.25mm毛刺。急性手术结局或急性对比剂肾病（CIN）发生率无显著差异，并且没有患者要求紧急CABG或在手术过程中死亡。主要不良心血管事件（MACE）无显著差异，医院两组之间的CVMACE或单个组件，在30、90和180天或1年。
未经评估：与倾向风险因素得分匹配的对照相比，手术并发症没有差异，acuteCIN或RA不同阶段CTO病变的临床结果。CTO患者的RA非常有效，并且显示出与非CTO病变相似的安全性和结局特征。
