慢性肾脏病和 NLRP3 炎性体 : 发病机制 ,发展和有针对性的治疗策略。
关键词: ,IL-18, Interleukin-18 ASC, apoptosis-associated speck-like protein Ang II, Angiotensin II CKD, Chronic kidney disease Chronic kidney disease DAMPs, damage-associated molecular patterns ESRD, End-stage renal disease GFR, glomerular filtration rate HK-2, renal tubular epithelial cells IL-1β, Interleukin-1β Inflammasome Kidney function LRR, leucine-rich repeat NEK7, NIMA-related kinase 7 NF-kB, nuclear factor kappa-B NLRP3, NLR family pyrin domain containing 3 NOD-like receptor PAMPs, Pathogen-associated molecular patterns ROS, reactive oxygen species TXNIP, thioredoxin-interacting protein
来 源:
DOI:10.1016/j.bbrep.2022.101417
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