关键词: Acute respiratory distress syndrome (ARDS) COVID-19 mortality multi-disciplinary pneumonia severity predictors

来  源:   DOI:10.4103/jfmpc.jfmpc_584_22   PDF(Pubmed)

Abstract:
UNASSIGNED: The mortality from coronavirus disease 2019 (COVID-19) infection and the severity of it vary among populations. There is a dearth of research on epidemiology and clinical outcomes in central Indian populations with COVID-19. Our aim was to provide an analysis of all hospitalized mortality among patients with COVID-19 infection in a tertiary care hospital of Chhattisgarh in central India. This analysis helped us to know the severity predictors for mortality and in future will help the authorities to formulate a plan to decrease the mortality in the epidemic or uncertain ongoing pandemic.
UNASSIGNED: This was a retrospective observational study using the hospital-based record of multi-disciplinary teaching hospital in Chhattisgarh, India. All COVID-19 reverse-transcriptase polymerase chain reaction-positive patients who were declared dead or died during the course of treatment from April 1, 2020 to March 31, 2021 were included in the study. In-hospital mortality was the primary outcome of interest. In secondary analysis, age and gender distribution, co-morbidity, length of stay, and the cause of death were also investigated.
UNASSIGNED: A total of 7495 patients with a confirmed diagnosis of COVID-19 were enrolled in the study, of whom 762 (10.16%) died in the hospital with COVID-19 as the primary cause of death. The majority of the patients were more than 60 years of age (45.7%). A total of 416 (54.4%) of the deceased patients were having co-morbidity with diabetes (13.4%), hypertension (16.4%), or both (24.4%). The majority of the patients who succumbed had a hospital stay of less than a week (≤7) (68.5%). More than half of the patients (58.3%) who expired had referred and reported to the hospital in the second or third week of illness. The respiratory system involvement was the dominant contributor of death with pneumonia (78.8%) being the most common cause, followed by acute respiratory distress syndrome (62.2%). 13.6% of expired patients had multiple system involvement, and 11.2% had sepsis as well.
UNASSIGNED: Mortality in COVID-19 patients was associated with advanced age, co-morbidities such as diabetes and hypertension, and delay in hospitalization. These are high-risk groups and should be vaccinated against COVID-19 on priority.
摘要:
未经证实:2019年冠状病毒病(COVID-19)感染的死亡率及其严重程度因人群而异。在患有COVID-19的印度中部人群中,缺乏流行病学和临床结果的研究。我们的目的是对印度中部恰蒂斯加尔邦三级保健医院中COVID-19感染患者的所有住院死亡率进行分析。这项分析帮助我们了解了死亡率的严重预测因素,并且将来将帮助当局制定一项计划,以降低该流行病或不确定的持续大流行中的死亡率。
UNASSIGNED:这是一项回顾性观察研究,使用恰蒂斯加尔邦多学科教学医院的医院记录,印度。在2020年4月1日至2021年3月31日的治疗过程中宣布死亡或死亡的所有COVID-19逆转录酶聚合酶链反应阳性患者均纳入研究。住院死亡率是感兴趣的主要结果。在次要分析中,年龄和性别分布,合并症,逗留时间,并调查了死因。
未经证实:共有7495名确诊为COVID-19的患者被纳入研究,其中762人(10.16%)在医院死亡,COVID-19是主要死亡原因。大多数患者年龄超过60岁(45.7%)。共有416例(54.4%)的死者患有糖尿病合并症(13.4%),高血压(16.4%),或两者(24.4%)。大多数死亡患者的住院时间少于一周(≤7)(68.5%)。超过一半的患者(58.3%)在患病的第二或第三周转诊并报告给医院。呼吸系统受累是死亡的主要原因,肺炎(78.8%)是最常见的原因。其次是急性呼吸窘迫综合征(62.2%)。13.6%的过期患者有多系统受累,11.2%也有脓毒症。
未经证实:COVID-19患者的死亡率与高龄有关,糖尿病和高血压等合并症,延误住院。这些是高危人群,应优先接种COVID-19疫苗。
公众号