Abstract:
In recent years, the benefits of carrots and carotene in different areas of health have been examined. The purpose of this umbrella review was to identify the associations between carrots and carotene and multiple health outcomes. The review considered evidence from meta-analyses of interventional and observational studies of carrots and carotene and any health outcome. We comprehensively searched Web of Science, PubMed, and Embase. For each association, we estimated the summary effect size using random and fixed effects models and the 95% confidence interval. A total of 1329 studies were searched, and 30 meta-analyses with 26 health outcomes were identified that met the eligibility criteria. Carrot intake was associated with a lower risk of multiple cancer outcomes including breast cancer, lung cancer, pancreatic cancer, gastric cancer, urothelial cancer, and prostate cancer. Carotene intake was associated with a lower risk of fracture, age-related cataract, sunburn, Alzheimer\'s disease, breast cancer, lung cancer, pancreatic cancer, gastric cancer, esophageal cancer, prostate cancer, and head and neck cancer (HNC). Serum carotene was inversely associated with all-cause mortality, breast cancer, and lung cancer. Our study revealed that carrot or carotene intake could reduce the risk of various negative health outcomes. © 2023 Society of Chemical Industry.
摘要:
背景:近年来,研究了胡萝卜和胡萝卜素在不同健康领域的益处。
目的:本综述的目的是确定胡萝卜和胡萝卜素与多种健康结果之间的关联。
方法:对胡萝卜和胡萝卜素的干预和观察研究以及任何健康结果的荟萃分析的证据进行综述。我们全面搜索了WebofScience,PubMed,和Embase。对于每个协会,我们使用随机效应和固定效应模型以及95%置信区间估计了总效应大小.
结果:共检索了1329项研究,通过资格标准确定了30项具有26项健康结果的荟萃分析。胡萝卜的摄入与包括乳腺癌在内的多种癌症预后的较低风险相关。肺癌,胰腺癌,胃癌,尿路上皮癌和前列腺癌.摄入胡萝卜素与较低的骨折风险相关,年龄相关性白内障,晒伤,老年痴呆症,乳腺癌,肺癌,胰腺癌,胃癌,食道癌,前列腺癌和头颈癌(HNC)。血清胡萝卜素与全因死亡率呈负相关,乳腺癌和肺癌。
结论:我们的研究表明,摄入胡萝卜或胡萝卜素可以降低各种健康结果的风险。本文受版权保护。保留所有权利。