关键词: ileal pouch anal anastomosis surgery total proctocolectomy ulcerative colitis

来  源:   DOI:10.1055/s-0042-1758134   PDF(Pubmed)

Abstract:
Ulcerative colitis (UC) requires surgical management in 20 to 30% of patients. Indications for surgery include medically refractory disease, dysplasia, cancer, and other complications of UC. Appropriate patient selection for timing and staging of surgery is paramount for optimal outcomes. Restorative proctocolectomy is the preferred standard of care and can afford many patients with excellent quality of life. There have been significant shifts in the treatment of UC-associated dysplasia, with less patients requiring surgery and more entering surveillance programs. There is ongoing controversy surrounding the management of UC-associated colorectal cancer and the techniques that should be used. This article reviews the most recent literature on the indications for elective and emergent surgical intervention for UC and the considerations behind the surgical options.
摘要:
溃疡性结肠炎(UC)需要20%至30%的患者进行手术治疗。手术适应症包括医学难治性疾病,发育不良,癌症,和UC的其他并发症。为手术的时机和分期选择合适的患者对于最佳结果至关重要。恢复性直肠结肠切除术是首选的护理标准,可以为许多患者提供出色的生活质量。UC相关发育不良的治疗有显著的转变,更少的患者需要手术和更多的进入监测计划。关于UC相关结直肠癌的治疗和应该使用的技术,一直存在争议。本文回顾了有关UC选择性和紧急手术干预的适应症以及手术选择背后的注意事项的最新文献。
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