PDF(Pubmed)
Abstract：
UNASSIGNED: Innovation is broadly defined as the act of introducing a new product, idea, or process. The field of surgery is built upon innovation, revolutionizing technology, science, and tools to improve patient care. While most innovative solutions are aimed at problems with a significant patient population, the process can also be used on orphan pathologies without obvious solutions. We present a case of tracheal agenesis, a rare congenital anomaly with an overwhelming mortality and few good treatment options, that benefited from the innovation process and achieved survival with no ventilator dependence at three years of age.
UNASSIGNED: Utilizing the framework of the innovation process akin to the Stanford Biodesign Program, 1) the parameters of the clinical problem were identified, 2) previous solutions and existing technologies were analyzed, newly invented solutions were brainstormed, and value analysis of the possible solutions were carried out using crowd wisdom, and 3) the selected solution was prototyped and tested using 3D modeling, iterative testing on 3D prints of actual-sized patient parts, and eventual implementation in the patient after regulatory clearance.
UNASSIGNED: A 3D-printed external bioresorbable splint was chosen as the solution. Our patient underwent airway reconstruction with \"trachealization of the esophagus\": esophageotracheal fistula resection, esophagotracheoplasty, and placement of a 3D-printed polycaprolactone (PCL) stent for external esophageal airway support at five months of age.
UNASSIGNED: The innovation process provided our team with the guidance and imperative steps necessary to develop an innovative device for the successful management of an infant survivor with Floyd Type I tracheal agenesis.
UNASSIGNED: We present a case of tracheal agenesis, a rare congenital anomaly with an overwhelming mortality and few good treatment options, that benefited from the innovation process and achieved survival with no ventilator dependence at three years of age.The importance of this report is to reveal how the innovation process, which is typically used for problems with significant patient population, can also be used on orphan pathologies without obvious solutions.
UNASSIGNED: Utilizing the framework of the innovation process akin to the Stanford Biodesign Program, 1) the parameters of the clinical problem were identified, 2) previous solutions and existing technologies were analyzed, newly invented solutions were brainstormed, and value analysis of the possible solutions were carried out using crowd wisdom, and 3) the selected solution was prototyped and tested using 3D modeling, iterative testing on 3D prints of actual-sized patient parts, and eventual implementation in the patient after regulatory clearance.
UNASSIGNED: A 3D-printed external bioresorbable splint was chosen as the solution. Our patient underwent airway reconstruction with \"trachealization of the esophagus\": esophageotracheal fistula resection, esophagotracheoplasty, and placement of a 3D-printed polycaprolactone (PCL) stent for external esophageal airway support at five months of age.
UNASSIGNED: The innovation process provided our team with the guidance and imperative steps necessary to develop an innovative device for the successful management of an infant survivor with Floyd Type I tracheal agenesis.
UNASSIGNED: We present a case of tracheal agenesis, a rare congenital anomaly with an overwhelming mortality and few good treatment options, that benefited from the innovation process and achieved survival with no ventilator dependence at three years of age.The importance of this report is to reveal how the innovation process, which is typically used for problems with significant patient population, can also be used on orphan pathologies without obvious solutions.
摘要：
未经评估：创新被广泛定义为引入新产品的行为，idea,或过程。外科领域建立在创新的基础上，革命性的技术，科学,以及改善病人护理的工具。虽然大多数创新的解决方案都是针对大量患者的问题，该过程也可以用于孤儿病理没有明显的解决方案。我们介绍一例气管发育不全,一种罕见的先天性异常，死亡率过高，几乎没有好的治疗选择，受益于创新过程，并在三岁时无呼吸机依赖的情况下获得了生存。
UNASSIGNED：利用类似于斯坦福生物设计计划的创新过程框架，1)确定了临床问题的参数，2)对以往的解决方案和现有技术进行了分析,新发明的解决方案被集思广益，并利用群体智慧对可能的解决方案进行了价值分析，3)使用3D建模对所选解决方案进行原型化和测试，对实际尺寸患者零件的3D打印进行迭代测试，并在监管许可后最终在患者中实施。
UNASSIGNED：选择3D打印的外部生物可吸收夹板作为解决方案。我们的患者接受了“食管气管化”的气道重建：食管气管瘘切除术，食管气管成形术,并在5个月大时放置3D打印的聚己内酯（PCL）支架用于食道外气道支持。
UNASSIGNED：创新过程为我们的团队提供了必要的指导和必要的步骤，以开发一种创新设备，以成功管理FloydI型气管发育不全的婴儿幸存者。
未经授权：我们介绍一例气管发育不全，一种罕见的先天性异常，死亡率过高，几乎没有好的治疗选择，受益于创新过程，并在三岁时无呼吸机依赖的情况下获得了生存。这份报告的重要性是揭示创新过程，通常用于大量患者群体的问题，也可以用于孤儿病理没有明显的解决方案。
UNASSIGNED：利用类似于斯坦福生物设计计划的创新过程框架，1)确定了临床问题的参数，2)对以往的解决方案和现有技术进行了分析,新发明的解决方案被集思广益，并利用群体智慧对可能的解决方案进行了价值分析，3)使用3D建模对所选解决方案进行原型化和测试，对实际尺寸患者零件的3D打印进行迭代测试，并在监管许可后最终在患者中实施。
UNASSIGNED：选择3D打印的外部生物可吸收夹板作为解决方案。我们的患者接受了“食管气管化”的气道重建：食管气管瘘切除术，食管气管成形术,并在5个月大时放置3D打印的聚己内酯（PCL）支架用于食道外气道支持。
UNASSIGNED：创新过程为我们的团队提供了必要的指导和必要的步骤，以开发一种创新设备，以成功管理FloydI型气管发育不全的婴儿幸存者。
未经授权：我们介绍一例气管发育不全，一种罕见的先天性异常，死亡率过高，几乎没有好的治疗选择，受益于创新过程，并在三岁时无呼吸机依赖的情况下获得了生存。这份报告的重要性是揭示创新过程，通常用于大量患者群体的问题，也可以用于孤儿病理没有明显的解决方案。
