Abstract：
OBJECTIVE: Breast cancer is the most lethal malignancy for women worldwide. Developed countries, such as Portugal, Spain, and the United States, have declining mortality rates due to breast cancer; however, in developing countries, the epidemiological reports are scarce. In this context, the aims of this study are to describe and discuss the female breast cancer profile of hospitalization and mortality according to age and geographic region in Brazil from 2008 to 2019.
METHODS: Data were obtained from the National Health System Department of Informatics (DATASUS), maintained by the Brazilian Ministry of Health, which includes the registers of hospitalization and mortality by malignant neoplasm of breast (code C50, ICD-10). Proportional rates of hospitalization and deaths were estimated per 100,000 inhabitants according to respective subjects\' age, region, and year of the occurrence.
RESULTS: From 2008 to 2019, 643,822 hospital admissions due to malignant neoplasm of breast were reported in Brazil, of which the South and Southeast regions were the most prevalent. Higher hospitalization rates were seen in subjects aged 50-79-years-old. Regarding mortality, 53,480 deaths by breast cancer were reported; similarly to hospitalization, the Southeast and South were the most affected regions. Mortality rates have increased over time in different magnitudes depending on subjects\' age.
CONCLUSIONS: We have shown an increase in morbidity and mortality over time, which is dependent on patients\' age and region. The results presented here may contribute to the ongoing discussion about the role and future perspectives of the Brazilian health care system, especially regarding to the strategies for the prevention, control, and treatment of breast cancer.
METHODS: Data were obtained from the National Health System Department of Informatics (DATASUS), maintained by the Brazilian Ministry of Health, which includes the registers of hospitalization and mortality by malignant neoplasm of breast (code C50, ICD-10). Proportional rates of hospitalization and deaths were estimated per 100,000 inhabitants according to respective subjects\' age, region, and year of the occurrence.
RESULTS: From 2008 to 2019, 643,822 hospital admissions due to malignant neoplasm of breast were reported in Brazil, of which the South and Southeast regions were the most prevalent. Higher hospitalization rates were seen in subjects aged 50-79-years-old. Regarding mortality, 53,480 deaths by breast cancer were reported; similarly to hospitalization, the Southeast and South were the most affected regions. Mortality rates have increased over time in different magnitudes depending on subjects\' age.
CONCLUSIONS: We have shown an increase in morbidity and mortality over time, which is dependent on patients\' age and region. The results presented here may contribute to the ongoing discussion about the role and future perspectives of the Brazilian health care system, especially regarding to the strategies for the prevention, control, and treatment of breast cancer.
摘要：
目的：乳腺癌是全世界女性最致命的恶性肿瘤。发达国家,比如葡萄牙,西班牙,和美国,由于乳腺癌的死亡率下降；然而，在发展中国家,流行病学报告很少。在这种情况下，本研究的目的是描述和讨论2008年至2019年巴西女性乳腺癌住院率和死亡率的情况.
方法：数据来自国家卫生系统信息学部（DATASUS），由巴西卫生部维护，其中包括住院和死亡的记录乳腺恶性肿瘤（代码C50，ICD-10）。根据受试者的年龄，每100,000名居民的住院率和死亡率按比例估算，区域,和发生的年份。
结果：从2008年到2019年，巴西报告了由于乳腺恶性肿瘤而住院的643,822例，其中南部和东南部地区最普遍。在50-79岁的受试者中观察到较高的住院率。关于死亡率，报告了53,480例乳腺癌死亡；类似于住院，东南部和南部是受影响最严重的地区。根据受试者的年龄，死亡率随着时间的推移以不同的幅度增加。
结论：我们已经显示出发病率和死亡率随着时间的推移而增加，这取决于患者的年龄和地区。这里提出的结果可能有助于正在进行的关于巴西医疗保健系统的作用和未来前景的讨论，特别是关于预防的策略，control,和治疗乳腺癌。
方法：数据来自国家卫生系统信息学部（DATASUS），由巴西卫生部维护，其中包括住院和死亡的记录乳腺恶性肿瘤（代码C50，ICD-10）。根据受试者的年龄，每100,000名居民的住院率和死亡率按比例估算，区域,和发生的年份。
结果：从2008年到2019年，巴西报告了由于乳腺恶性肿瘤而住院的643,822例，其中南部和东南部地区最普遍。在50-79岁的受试者中观察到较高的住院率。关于死亡率，报告了53,480例乳腺癌死亡；类似于住院，东南部和南部是受影响最严重的地区。根据受试者的年龄，死亡率随着时间的推移以不同的幅度增加。
结论：我们已经显示出发病率和死亡率随着时间的推移而增加，这取决于患者的年龄和地区。这里提出的结果可能有助于正在进行的关于巴西医疗保健系统的作用和未来前景的讨论，特别是关于预防的策略，control,和治疗乳腺癌。
