Abstract：
BACKGROUND: Accurate preoperative diagnosis of neurovascular compression (NVC) is crucial in the treatment of trigeminal neuralgia (TN) or hemifacial spasm (HFS). At present, there are many magnetic resonance imaging (MRI)-based methods for diagnosing NVC in clinical practice. This network meta-analysis (NMA) aimed to evaluate the diagnostic performance of different MRI-based imaging methods for NVC in patients with TN and HFS.
METHODS: Related studies based on a search of PubMed, Embase, Web of Science and the Cochrane Library were retrieved. A two-way analysis of variance model was constructed for the Bayesian NMA to compare the performance of different diagnostic imaging methods.
RESULTS: Our search identified 595 articles, of which 26 studies (including 2085 patients) related to 4 diagnostic imaging methods (3D time-of-flight magnetic resonance angiography (3D TOF MRA), high resolution T2-weighted imaging (HR T2WI), 3D TOF MRA combined with HR T2WI, and 3D multimodal image fusion (MIF) based on 3D TOF MRA combined with HR T2WI) were included in this NMA. The results showed that 3D MIF based on 3D TOF MRA combined with HR T2WI had the highest related sensitivity, the highest superiority index and the largest area under the receiver operating characteristic curve among all the methods.
CONCLUSIONS: 3D MIF based on 3D TOF MRA combined with HR T2WI had better diagnostic performance for detecting NVC in patients with TN or HSF than other MRI-based imaging methods. This method can be used as an effective tool for preoperative evaluation of MVD.
METHODS: Related studies based on a search of PubMed, Embase, Web of Science and the Cochrane Library were retrieved. A two-way analysis of variance model was constructed for the Bayesian NMA to compare the performance of different diagnostic imaging methods.
RESULTS: Our search identified 595 articles, of which 26 studies (including 2085 patients) related to 4 diagnostic imaging methods (3D time-of-flight magnetic resonance angiography (3D TOF MRA), high resolution T2-weighted imaging (HR T2WI), 3D TOF MRA combined with HR T2WI, and 3D multimodal image fusion (MIF) based on 3D TOF MRA combined with HR T2WI) were included in this NMA. The results showed that 3D MIF based on 3D TOF MRA combined with HR T2WI had the highest related sensitivity, the highest superiority index and the largest area under the receiver operating characteristic curve among all the methods.
CONCLUSIONS: 3D MIF based on 3D TOF MRA combined with HR T2WI had better diagnostic performance for detecting NVC in patients with TN or HSF than other MRI-based imaging methods. This method can be used as an effective tool for preoperative evaluation of MVD.
摘要：
背景：术前准确诊断神经血管压迫（NVC）对于三叉神经痛（TN）或面肌痉挛（HFS）的治疗至关重要。目前,在临床实践中，有许多基于磁共振成像（MRI）的诊断NVC的方法。这项网络荟萃分析（NMA）旨在评估基于MRI的不同成像方法对TN和HFS患者NVC的诊断性能。
方法：基于PubMed搜索的相关研究，Embase,检索了WebofScience和Cochrane图书馆。为贝叶斯NMA构建了双向方差分析模型，以比较不同诊断成像方法的性能。
结果：我们的搜索发现了595篇文章，其中26项研究（包括2085例患者）涉及4种诊断成像方法（3D飞行时间磁共振血管造影（3DTOFMRA），高分辨率T2加权成像（HRT2WI），3DTOFMRA结合HRT2WI，该NMA包括基于3DTOFMRA和HRT2WI的3D多模态图像融合（MIF）。结果表明，基于3DTOFMRA结合HRT2WI的3DMIF具有最高的相关灵敏度，在所有方法中，优势指数最高，接受者工作特性曲线下面积最大。
结论：基于3DTOFMRA结合HRT2WI的3DMIF在检测TN或HSF患者的NVC方面比其他基于MRI的成像方法具有更好的诊断性能。该方法可作为术前评估MVD的有效工具。
方法：基于PubMed搜索的相关研究，Embase,检索了WebofScience和Cochrane图书馆。为贝叶斯NMA构建了双向方差分析模型，以比较不同诊断成像方法的性能。
结果：我们的搜索发现了595篇文章，其中26项研究（包括2085例患者）涉及4种诊断成像方法（3D飞行时间磁共振血管造影（3DTOFMRA），高分辨率T2加权成像（HRT2WI），3DTOFMRA结合HRT2WI，该NMA包括基于3DTOFMRA和HRT2WI的3D多模态图像融合（MIF）。结果表明，基于3DTOFMRA结合HRT2WI的3DMIF具有最高的相关灵敏度，在所有方法中，优势指数最高，接受者工作特性曲线下面积最大。
结论：基于3DTOFMRA结合HRT2WI的3DMIF在检测TN或HSF患者的NVC方面比其他基于MRI的成像方法具有更好的诊断性能。该方法可作为术前评估MVD的有效工具。
