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Abstract：
Nowadays, viral infection is considered a major cause of mortality all over the world such as covid-19 pandemic. In this context, searching for antiviral agents are major researchers interests. In this study, essential oils (EO) of Lavandula angustifolia (lavender) and Salvia officinalis (salvia) were subjected to combat avian influenza H5N1 virus. Laboratory trials were performed to identify Lavender and salvia EOs and evaluate their antioxidant, anti-inflammatory and antiviral activity against an avian influenza H5N1 virus. EOs were prepared by the hydrodistillation of air-dried plants and analyzed by GC-MS methods. The results revealed that salvia has the highest EOs yield 1.3% than lavender 1%. The dominant constituents of lavender EO were linalyl acetate and linalool while camphor and α-thujone were the dominant compounds of salvia. Both oils exhibited antioxidant activity in DPPH and ABTS and total antioxidant capacity assays. The results suggest the use of salvia and lavender EOs as effective natural anti-inflammatory, antioxidant and antiviral agents.
摘要：
如今,病毒感染被认为是全世界死亡的主要原因，如covid-19大流行。在这种情况下，寻找抗病毒药物是研究人员的主要兴趣。在这项研究中,薰衣草（薰衣草）和丹参（丹参）的精油（EO）与禽流感H5N1病毒作斗争。进行实验室试验以鉴定薰衣草和丹参EO并评估其抗氧化剂，抗H5N1禽流感病毒的抗炎和抗病毒活性。EO是通过空气干燥的植物的加氢蒸馏制备的，并通过GC-MS方法进行分析。结果表明，丹参的EO产量最高，为1.3%，而薰衣草为1%。薰衣草EO的主要成分是醋酸芳酯和芳樟醇，而樟脑和α-thujone是丹参的主要成分。两种油在DPPH和ABTS以及总抗氧化能力测定中均表现出抗氧化活性。结果表明，使用丹参和薰衣草EO作为有效的天然抗炎，抗氧化剂和抗病毒剂。
