PDF(Pubmed)
Abstract：
Relapsing polychondritis (RP) most commonly presents as inflammation and degeneration of cartilaginous tissue in the auricles, nasal septum, and lungs (in severe instances). RP is a rare autoimmune condition associated with other autoimmune diseases in 30% of cases. The prevalence of gastrointestinal involvement with RP is tenuous; however, there is a growing collection of case studies associating auricular chondritis with concomitant inflammatory bowel disease (IBD), including both ulcerative colitis and Crohn\'s disease. We report the case of a 35-year-old patient presenting with autoimmune pancreatitis, with a past medical history of Crohn\'s disease, primary sclerosing cholangitis (PSC), and suspected RP. Although RP is rare, the disease\'s multiple clinical presentations and recurrent episodic nature can cause significant diagnostic delays and are often overlooked by physicians. Thus, low disease prevalence may be due to under-recognition and under-reporting of disease symptoms. As RP is a clinical diagnosis, increased awareness of the disease presentation and clinical characteristics may increase disease recognition and improve treatment outcomes.
摘要：
复发性多软骨炎（RP）最常表现为耳廓软骨组织的炎症和变性，鼻中隔,和肺（在严重的情况下）。在30％的病例中，RP是与其他自身免疫性疾病相关的罕见自身免疫性疾病。胃肠道受累RP的患病率是微弱的；然而，越来越多的案例研究将耳廓软骨炎与并发炎症性肠病（IBD）相关联，包括溃疡性结肠炎和克罗恩病。我们报告了一例35岁的患者出现自身免疫性胰腺炎，有克罗恩病的病史,原发性硬化性胆管炎（PSC），怀疑RP。虽然RP是罕见的，该疾病的多临床表现和反复发作性可导致严重的诊断延迟，并经常被医生忽视。因此，低患病率可能是由于对疾病症状的认识不足和报告不足.由于RP是一种临床诊断，提高对疾病表现和临床特征的认识可能会提高对疾病的认识并改善治疗结果.
