PDF(Pubmed)
Abstract：
UNASSIGNED: To examine the association of hypertension (HBP) and its control with atrial fibrillation (AF) and how patient sex affects this association.
UNASSIGNED: A case control study of patients admitted to our hospital from 2015 to 2019 was conducted. Patients were divided into subgroups according to their blood pressure (BP) levels and control status, in which odd ratios (OR) by sex for AF was estimated using a logistic regression model and restrictive cubic splines before and after propensity score matching.
UNASSIGNED: A total of 3,212 patients with AF and 8,307 without AF were investigated. Compared to patients with normal BP, patients with HBP had more AF [OR = 1.75 (1.52-2.02), OR = 2.66 (2.24-3.15), and OR = 4.30 (3.40-5.44) in patients with grade 1, 2, and 3 HBP, respectively]. In HBP patients with grade 3, the OR of AF was much higher in women than in men (OR = 7.15, 95% CI: 4.43-11.50 vs. OR = 2.48, 95% CI: 1.66-3.72). BP over 133.1/79.9 mmHg in men or 127.1/75.1 mmHg in women was positively associated with AF. In patients with HBP, uncontrolled BP was more associated with AF (OR = 3.00, 95% CI: 2.53-3.56), especially in women (OR = 3.09, 95% CI: 2.27-4.19). BP and prevalence of AF correlated with each other positively in patients admitted to a cardiology ward. Lowering BP to 145.1/85.8 mmHg in men or 140.5/82.5 mmHg in women led to less AF.
UNASSIGNED: There is more significant relationship between HBP and AF in female patients. A lower and individualized BP target may be formulated to prevent AF in women.
UNASSIGNED: A case control study of patients admitted to our hospital from 2015 to 2019 was conducted. Patients were divided into subgroups according to their blood pressure (BP) levels and control status, in which odd ratios (OR) by sex for AF was estimated using a logistic regression model and restrictive cubic splines before and after propensity score matching.
UNASSIGNED: A total of 3,212 patients with AF and 8,307 without AF were investigated. Compared to patients with normal BP, patients with HBP had more AF [OR = 1.75 (1.52-2.02), OR = 2.66 (2.24-3.15), and OR = 4.30 (3.40-5.44) in patients with grade 1, 2, and 3 HBP, respectively]. In HBP patients with grade 3, the OR of AF was much higher in women than in men (OR = 7.15, 95% CI: 4.43-11.50 vs. OR = 2.48, 95% CI: 1.66-3.72). BP over 133.1/79.9 mmHg in men or 127.1/75.1 mmHg in women was positively associated with AF. In patients with HBP, uncontrolled BP was more associated with AF (OR = 3.00, 95% CI: 2.53-3.56), especially in women (OR = 3.09, 95% CI: 2.27-4.19). BP and prevalence of AF correlated with each other positively in patients admitted to a cardiology ward. Lowering BP to 145.1/85.8 mmHg in men or 140.5/82.5 mmHg in women led to less AF.
UNASSIGNED: There is more significant relationship between HBP and AF in female patients. A lower and individualized BP target may be formulated to prevent AF in women.
摘要：
UNASSIGNED：研究高血压（HBP）及其控制与心房颤动（AF）的相关性，以及患者性别如何影响这种相关性。
UNASSIGNED：对我院2015年至2019年收治的患者进行病例对照研究。根据患者血压（BP）水平和控制状态分为亚组，在倾向评分匹配前后,使用逻辑回归模型和限制性三次样条估计房颤按性别划分的奇数比(OR)。
未经证实：共调查了3,212例房颤患者和8,307例无房颤患者。与血压正常的患者相比，HBP患者有更多的AF[OR=1.75（1.52-2.02），OR=2.66（2.24-3.15），1、2、3级HBP患者的OR=4.30(3.40-5.44)，分别]。在3级HBP患者中，女性房颤的OR远高于男性（OR=7.15，95％CI：4.43-11.50vs.OR=2.48，95%CI：1.66-3.72）。男性血压超过133.1/79.9mmHg或女性血压超过127.1/75.1mmHg与房颤呈正相关。在HBP患者中，血压失控与房颤的相关性更高(OR=3.00,95%CI:2.53-3.56),尤其是女性（OR=3.09，95%CI：2.27-4.19）。在入住心脏病病房的患者中，BP和AF的患病率呈正相关。男性血压降至145.1/85.8mmHg或女性血压降至140.5/82.5mmHg导致房颤减少。
UASSIGNED：女性患者中HBP与AF的关系更显著。可以制定较低和个性化的BP目标以预防女性AF。
UNASSIGNED：对我院2015年至2019年收治的患者进行病例对照研究。根据患者血压（BP）水平和控制状态分为亚组，在倾向评分匹配前后,使用逻辑回归模型和限制性三次样条估计房颤按性别划分的奇数比(OR)。
未经证实：共调查了3,212例房颤患者和8,307例无房颤患者。与血压正常的患者相比，HBP患者有更多的AF[OR=1.75（1.52-2.02），OR=2.66（2.24-3.15），1、2、3级HBP患者的OR=4.30(3.40-5.44)，分别]。在3级HBP患者中，女性房颤的OR远高于男性（OR=7.15，95％CI：4.43-11.50vs.OR=2.48，95%CI：1.66-3.72）。男性血压超过133.1/79.9mmHg或女性血压超过127.1/75.1mmHg与房颤呈正相关。在HBP患者中，血压失控与房颤的相关性更高(OR=3.00,95%CI:2.53-3.56),尤其是女性（OR=3.09，95%CI：2.27-4.19）。在入住心脏病病房的患者中，BP和AF的患病率呈正相关。男性血压降至145.1/85.8mmHg或女性血压降至140.5/82.5mmHg导致房颤减少。
UASSIGNED：女性患者中HBP与AF的关系更显著。可以制定较低和个性化的BP目标以预防女性AF。
