Abstract：
To describe the prevalence, distribution, and features of anterior and posterior segment abnormalities in the contralateral eye in cases unilateral of anophthalmia and blind microphthalmia.
The medical records of patients with unilateral congenital anophthalmia and blind microphthalmia referred to Beijing Tongren Hospital between January 2017 and December 2021 were reviewed retrospectively to investigate the prevalence of abnormalities of the fellow eye.
A total of 168 patients were included. Of these, 28 (16.7%) had fellow eye abnormalities, 4 (2.4%) with anterior segment involvement in the contralateral eye. All 28 had fundus abnormalities. The most common posterior segment finding was coloboma (7.7%), followed by optic nerve dysplasia (3.0%), familial exudative vitreoretinopathy (FEVR) or FEVR-like fundus (1.8%), morning glory disk anomaly (1.8%), and retinal nerve fiber layer defect (1.2%). High myopia fundus changes (0.6%), retinal folds (0.6%), maculopathy (0.6%), peripapillary staphyloma (0.6%), and Bergmeister optic disk (0.6%) were also noted.
Patients with unilateral congenital anophthalmia or blind microphthalmia have a high probability of contralateral eye disease. The most common abnormality is coloboma.
The medical records of patients with unilateral congenital anophthalmia and blind microphthalmia referred to Beijing Tongren Hospital between January 2017 and December 2021 were reviewed retrospectively to investigate the prevalence of abnormalities of the fellow eye.
A total of 168 patients were included. Of these, 28 (16.7%) had fellow eye abnormalities, 4 (2.4%) with anterior segment involvement in the contralateral eye. All 28 had fundus abnormalities. The most common posterior segment finding was coloboma (7.7%), followed by optic nerve dysplasia (3.0%), familial exudative vitreoretinopathy (FEVR) or FEVR-like fundus (1.8%), morning glory disk anomaly (1.8%), and retinal nerve fiber layer defect (1.2%). High myopia fundus changes (0.6%), retinal folds (0.6%), maculopathy (0.6%), peripapillary staphyloma (0.6%), and Bergmeister optic disk (0.6%) were also noted.
Patients with unilateral congenital anophthalmia or blind microphthalmia have a high probability of contralateral eye disease. The most common abnormality is coloboma.
摘要：
目的：描述患病率，分布，在单侧无眼和盲性小眼症中，对侧眼的前后节异常的特征。
方法：回顾性分析2017年1月至2021年12月北京同仁医院收治的单侧先天性无眼和盲性小眼患者的病历资料，调查同眼畸形的患病率。
结果：共纳入168例患者。其中,28人(16.7%)有同伴眼睛异常，4例（2.4％），对侧眼眼前节受累。所有28名患者均有眼底异常。最常见的后段发现是结肠缺损（7.7％），其次是视神经发育不良(3.0%)，家族性渗出性玻璃体视网膜病变（FEVR）或FEVR样眼底（1.8％），牵牛花盘异常(1.8%),视网膜神经纤维层缺损(1.2%)。高度近视眼底改变(0.6%),视网膜褶皱（0.6%），黄斑病变（0.6%），乳头周围葡萄肿（0.6%），和Bergmeister视盘（0.6%）也被注意到。
结论：患有单侧先天性无眼或盲性小眼的患者发生对侧眼病的概率很高。最常见的异常是结肠瘤。
方法：回顾性分析2017年1月至2021年12月北京同仁医院收治的单侧先天性无眼和盲性小眼患者的病历资料，调查同眼畸形的患病率。
结果：共纳入168例患者。其中,28人(16.7%)有同伴眼睛异常，4例（2.4％），对侧眼眼前节受累。所有28名患者均有眼底异常。最常见的后段发现是结肠缺损（7.7％），其次是视神经发育不良(3.0%)，家族性渗出性玻璃体视网膜病变（FEVR）或FEVR样眼底（1.8％），牵牛花盘异常(1.8%),视网膜神经纤维层缺损(1.2%)。高度近视眼底改变(0.6%),视网膜褶皱（0.6%），黄斑病变（0.6%），乳头周围葡萄肿（0.6%），和Bergmeister视盘（0.6%）也被注意到。
结论：患有单侧先天性无眼或盲性小眼的患者发生对侧眼病的概率很高。最常见的异常是结肠瘤。
